Anti-inflammatory therapeutic mechanisms of natural products: insight from rosemary diterpenes, carnosic acid and carnosol

S Habtemariam - Biomedicines, 2023 - mdpi.com
Carnosic acid (CA) and carnosol (CAR) are two major diterpenes of the rosemary plant
(Rosmarinus officinalis). They possess a phenolic structural moiety and are endowed with …

Isolation and biological activity of natural chalcones based on antibacterial mechanism classification

S Wang, C Li, L Zhang, B Sun, Y Cui, F Sang - Bioorganic & Medicinal …, 2023 - Elsevier
Bacterial infection, which is still one of the leading causes of death in humans, poses an
enormous threat to the worldwide public health system. Antibiotics are the primary …

Functionalization of Polyhydroxyalkanoates (PHA)-based bioplastic with Phloretin for active food packaging: characterization of its mechanical, antioxidant, and …

SF Mirpoor, GT Patanè, I Corrado… - International Journal of …, 2023 - mdpi.com
The formulation of eco-friendly biodegradable packaging has received great attention during
the last decades as an alternative to traditional widespread petroleum-based food …

Phloretin alleviates palmitic acid-induced oxidative stress in HUVEC cells by suppressing the expression of LncBAG6-AS

J Li, Q Yang, H Liu, M Wang, C Pan, L Han, X Lan - Food & Function, 2023 - pubs.rsc.org
Oxidative stress (OS) is an important trigger of vascular endothelial injury (VEI), which then
leads to cardiovascular disease (CVDs). Phloretin was previously investigated to alleviate …

[HTML][HTML] SGLT2 inhibitors: Beyond glycemic control

I Hasan, T Rashid, V Jaikaransingh, C Heilig… - Journal of Clinical & …, 2024 - Elsevier
Multiple randomized controlled trials have extensively examined the therapeutic
effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors, ushering in a …

Formulation, characterization, pharmacokinetics and antioxidant activity of phloretin oral granules

RD Deshpande, DS Shah, S Gurram, DK Jha… - International Journal of …, 2023 - Elsevier
Phloretin (PHL), a flavonoid of the dihydrogen chalcone class, is reported to have low oral
bioavailability due to its poor solubility and absorption. A common approach to enhance the …

Averrhoa carambola L. fruit and stem metabolites profiling and immunostimulatory action mechanisms against cyclosporine induced toxic effects in rat model as …

NS Ramadan, NM Fayek, MM El-Sayed… - Food and Chemical …, 2023 - Elsevier
The Averrhoa carambola L. tree encompasses a myriad of phytochemicals contributing to its
nutritional and health benefits. The current study aims at investigating the A. carambola L …

Antimicrobial Effect of Honey Phenolic Compounds against E. coli—An In Vitro Study

L Kassym, A Kussainova, Y Semenova, P McLoone - Pharmaceuticals, 2024 - mdpi.com
Growing concern over antimicrobial resistance in chronic wound patients necessitates the
exploration of alternative treatments from natural sources. This study suggests that honey's …

Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo …

X Zhang, L Li, J Chen, M Hu, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Cynomorium songaricum Rupr. has long been used as an anti-inflammatory,
antidepressant, and anti-aging agent in traditional Chinese medicine in Asia. Its ethyl …

An intelligent controlled release hydrogel with photothermal effect for the treatment of bone defects

H Wei, T Zhao, X Liu, Q Ding, S Zhang, J Yang… - Chemical Engineering …, 2024 - Elsevier
To solve the difficulty of natural healing in patients with severe bone defects, and the
challenges of insufficient autologous bone graft material and large incisions in conventional …