The aim of this study was to evaluate the impact of early treatment with corticosteroids on
SARS-CoV-2 clearance in hospitalized COVID-19 patients. Retrospective analysis on …

The past two centuries have seen enormous achievements in control of infectious diseases,
previously the leading cause of death, in large measure due to sanitation and food safety …

Background Excess mortality due to seasonal influenza is substantial, yet quantitative
estimates of the benefit of annual vaccination programs on influenza-associated mortality …

Clin Microbiol Infect 2012; 18 (Suppl. 5): 100–108 Abstract Vaccination is the most efficient
strategy to prevent infectious disease. The increased vulnerability to infection of the elderly …

Seasonal influenza outbreaks, especially in high-risk groups such as the elderly, represent
an important public health problem. Prevailing inadequate efficacy of seasonal vaccines is a …

Background: The gut microbiota plays an essential role in human health. Toward seniority,
its balance is affected by deep physiological changes. Long-lived people (age> 90 y) have …

Highlights•The majority of the Dutch population (1–90 years of age) has parenteral and
Omicron SARS-CoV-2–specific mucosal immunoglobulin (Ig) G antibodies.•The presence of …

Ovariectomy in rodents is a good model for mimicking human ovarian hormone loss. This
work studies the consequences of ovariectomy on the nervous and immune systems in the …

Aging is associated with a decline in B-lymphopoiesis in the bone marrow and accumulation
of long-lived B cells in the periphery. These changes decrease the body's ability to mount …

West Nile virus (WNV) is an emerging pathogen that is now the leading cause of mosquito-
borne and epidemic encephalitis in the United States. In humans, a small percentage of …