[HTML][HTML] Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data
Liquid chromatography coupled with high-resolution mass spectrometry (LC–HRMS) has
become a workhorse in global metabolomics studies with growing applications across …
become a workhorse in global metabolomics studies with growing applications across …
Multi-omics integration in biomedical research–A metabolomics-centric review
Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …
layers of a biological system, including DNA sequence data (genomics), RNA expression …
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
Since its first release over a decade ago, the MetaboAnalyst web-based platform has
become widely used for comprehensive metabolomics data analysis and interpretation …
become widely used for comprehensive metabolomics data analysis and interpretation …
Using MetaboAnalyst 4.0 for comprehensive and integrative metabolomics data analysis
Abstract MetaboAnalyst (https://www. metaboanalyst. ca) is an easy‐to‐use web‐based tool
suite for comprehensive metabolomic data analysis, interpretation, and integration with other …
suite for comprehensive metabolomic data analysis, interpretation, and integration with other …
[HTML][HTML] MetaboAnalystR 3.0: toward an optimized workflow for global metabolomics
Liquid chromatography coupled to high-resolution mass spectrometry platforms are
increasingly employed to comprehensively measure metabolome changes in systems …
increasingly employed to comprehensively measure metabolome changes in systems …
[HTML][HTML] Mitochondrial integrated stress response controls lung epithelial cell fate
Abstract Alveolar epithelial type 1 (AT1) cells are necessary to transfer oxygen and carbon
dioxide between the blood and air. Alveolar epithelial type 2 (AT2) cells serve as a partially …
dioxide between the blood and air. Alveolar epithelial type 2 (AT2) cells serve as a partially …
[HTML][HTML] Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
RL Allesøe, AT Lundgaard, R Hernández Medina… - Nature …, 2023 - nature.com
The application of multiple omics technologies in biomedical cohorts has the potential to
reveal patient-level disease characteristics and individualized response to treatment …
reveal patient-level disease characteristics and individualized response to treatment …
[HTML][HTML] MetaboAnalystR 2.0: from raw spectra to biological insights
Global metabolomics based on high-resolution liquid chromatography mass spectrometry
(LC-MS) has been increasingly employed in recent large-scale multi-omics studies …
(LC-MS) has been increasingly employed in recent large-scale multi-omics studies …
[HTML][HTML] Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease
MI Hernández-Alvarez, D Sebastián, S Vives… - Cell, 2019 - cell.com
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the
mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 …
mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 …
[HTML][HTML] What is new in the exposome?
P Vineis, O Robinson, M Chadeau-Hyam… - Environment …, 2020 - Elsevier
The exposome concept refers to the totality of exposures from a variety of external and
internal sources including chemical agents, biological agents, or radiation, from conception …
internal sources including chemical agents, biological agents, or radiation, from conception …