[HTML][HTML] Sequence-Based Platforms for Discovering Biomarkers in Liquid Biopsy of Non-Small-Cell Lung Cancer

LJ Brockley, VGP Souza, A Forder, ME Pewarchuk… - Cancers, 2023 - mdpi.com
Simple Summary A lack of sensitive biomarkers hinders lung cancer detection and
monitoring, resulting in late diagnosis and missed treatment response. Liquid biopsies have …

[HTML][HTML] Clinical application of liquid biopsy based on circulating tumor DNA in non-small cell lung cancer

L Xin, Y Yue, R Zihan, C Youbin, L Tianyu… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is a widely occurring and deadly malignancy, with high prevalence rates in
China and across the globe. Specifically, non-small cell lung cancer (NSCLC) represents …

[HTML][HTML] Liquid biopsy in early-stage lung cancer: Current and Future Clinical Applications

O Vandekerckhove, K Cuppens, K Pat, B Du Pont… - Cancers, 2023 - mdpi.com
Simple Summary Early-stage disease non-small cell lung cancer has better outcomes than
advanced disease, but 5-year survival rates can drop to approximately 50% in cases of …

[HTML][HTML] Current and emerging applications of liquid biopsy in pan-cancer

W Wang, Y He, F Yang, K Chen - Translational Oncology, 2023 - Elsevier
Cancer morbidity and mortality are growing rapidly worldwide and it is urgent to develop a
convenient and effective method that can identify cancer patients at an early stage and …

[HTML][HTML] A unique circulating microRNA pairs signature serves as a superior tool for early diagnosis of pan-cancer

P Wu, D Li, C Zhang, B Dai, X Tang, J Liu, Y Wu… - Cancer Letters, 2024 - Elsevier
Cancer remains a major burden globally and the critical role of early diagnosis is self-
evident. Although various miRNA-based signatures have been developed in past decades …

Sandwich Immuno-RCA Assay with Single Molecule Counting Readout: The Importance of Biointerface Design

K Schmidt, T Riedel… - … Applied Materials & …, 2024 - ACS Publications
The analysis of low-abundance protein molecules in human serum is reported based on
counting of the individual affinity-captured analyte on a solid sensor surface, yielding a …

[HTML][HTML] Towards the molecular era of discriminating multiple lung cancers

Z Wang, X Yuan, G Jiang, Y Li, F Yang, J Wang… - …, 2023 - thelancet.com
In the era of histopathology-based diagnosis, the discrimination between multiple lung
cancers (MLCs) poses significant uncertainties and has thus become a clinical dilemma …

[HTML][HTML] Development of new techniques and clinical applications of liquid biopsy in lung cancer management

K Chen, Y He, W Wang, X Yuan, DP Carbone, F Yang - Science Bulletin, 2024 - Elsevier
Lung cancer is an exceedingly malignant tumor reported as having the highest morbidity
and mortality of any cancer worldwide, thus posing a great threat to global health. Despite …

[HTML][HTML] Biomarkers: a new frontier in lung cancer detection

J Pura-Bryant, JA Olivera… - Translational Lung Cancer …, 2024 - ncbi.nlm.nih.gov
© Translational Lung Cancer Research. All rights reserved. Transl Lung Cancer Res 2024;
13 (1): 210-212| https://dx. doi. org/10.21037/tlcr-23-801 namely peripheral biomarkers. Both …

[HTML][HTML] Variant Allele Frequency Analysis of Circulating Tumor DNA as a Promising Tool in Assessing the Effectiveness of Treatment in Non-Small Cell Lung …

N Galant, M Nicoś, B Kuźnar-Kamińska, P Krawczyk - Cancers, 2024 - mdpi.com
Simple Summary The non-invasive characteristic of liquid biopsy enables an increase in the
potential of VAF analysis in monitoring tumor progression, remission, and recurrence during …