Natural history of COVID-19 and therapeutic options

P Gautret, M Million, PA Jarrot… - Expert review of …, 2020 - Taylor & Francis
Introduction: COVID-19 presents benign forms in young patients who frequently present with
anosmia. Infants are rarely infected, while severe forms occur in patients over 65 years of …

Factors associated for mortality of older people with COVID 19: a systematic review and meta-analysis

H Damayanthi, KIP Prabani… - … and Geriatric Medicine, 2021 - journals.sagepub.com
Background Whilst people of all ages are affected in some way by COVID-19 virus, older
people are at a high mortality risk. This study aimed to systematically review the numerous …

Association of pre-existing comorbidities with mortality and disease severity among 167,500 individuals with COVID-19 in Canada: A population-based cohort study

E Ge, Y Li, S Wu, E Candido, X Wei - PLoS One, 2021 - journals.plos.org
Background The novel coronavirus disease 2019 (COVID-19) has infected 1.9% of the world
population by May 2, 2021. Since most previous studies that examined risk factors for …

[HTML][HTML] COVID-19 is associated with oropharyngeal dysphagia and malnutrition in hospitalized patients during the spring 2020 wave of the pandemic

A Martin–Martinez, O Ortega, P Viñas, V Arreola… - Clinical Nutrition, 2022 - Elsevier
Background and aims Prevalence and complications of oropharyngeal dysphagia (OD) and
malnutrition (MN) in COVID-19 patients is unknown. Our aim was to assess the prevalence …

Non‐pharmacological measures implemented in the setting of long‐term care facilities to prevent SARS‐CoV‐2 infections and their consequences: a rapid review

JM Stratil, RL Biallas, J Burns, L Arnold… - Cochrane Database …, 2021 - cochranelibrary.com
Background Starting in late 2019, COVID‐19, caused by the novel coronavirus SARS‐CoV‐
2, spread around the world. Long‐term care facilities are at particularly high risk of …

[HTML][HTML] Early combination therapy with hydroxychloroquine and azithromycin reduces mortality in 10,429 COVID-19 outpatients

M Million, JC Lagier, H Tissot-Dupont… - Reviews in …, 2021 - imrpress.com
We evaluated the age-specific mortality of unselected adult outpatients infected with SARS-
CoV-2 treated early in a dedicated COVID-19 day hospital and we assessed whether the …

Frailty assessment in the emergency department for risk stratification of COVID-19 patients aged≥ 80 years

M Covino, A Russo, S Salini, G De Matteis… - Journal of the American …, 2021 - Elsevier
Objectives To evaluate, in a cohort of adults aged≥ 80 years, the overlapping effect of
clinical severity, comorbidities, cognitive impairment, and frailty, for the in-hospital death risk …

Predictors of in-hospital mortality AND death RISK STRATIFICATION among COVID-19 PATIENTS aged≥ 80 YEARs OLD

M Covino, G De Matteis, DA Della Polla… - Archives of gerontology …, 2021 - Elsevier
Introduction: To date, mainly due to age-related vulnerability and to coexisting comorbidities,
older patients often face a more severe COVID-19. This study aimed to identify at …

Risk factors for COVID-19 morbidity and mortality in institutionalised elderly people

A Burgaña Agoües, M Serra Gallego… - International journal of …, 2021 - mdpi.com
Background: SARS-CoV-2 has caused a high mortality in institutionalised individuals. There
are very few studies on the involvement and the real impact of COVID-19 in nursing homes …

Early multidrug treatment of SARS-CoV-2 infection (COVID-19) and reduced mortality among nursing home (or outpatient/ambulatory) residents

PE Alexander, R Armstrong, G Fareed, J Lotus… - Medical hypotheses, 2021 - Elsevier
The outbreak of COVID-19 from severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread all over the world with tremendous morbidity and mortality in the elderly …