Geriatricians and others must embrace the emerging field of geroscience. Until recently
geroscience research was pursued in laboratory animals, but now this field requires …

To define metrics of phenotypic aging, it is essential to identify biological and environmental
factors that influence the pace of aging. Previous attempts to develop aging metrics were …

Background It is known that some people age faster than others, some people live into old
age disease-free, while others develop age-related chronic diseases. With a rapidly aging …

Middle age has historically been an understudied period of life compared to older age, when
cognitive and brain health decline are most pronounced, but the scope for intervention may …

Importance The Dunedin Pace of Aging Calculated From the Epigenome (DunedinPACE)
measure is a newly constructed DNA methylation (DNAm) biomarker associated with …

Dietary intervention is a safe, broad-spectrum, and low-cost preventive strategy for slow
aging. The Okinawan, Mediterranean, and Dietary approaches to stop hypertension (DASH) …

The significance of diversity, composition, and functional attributes of the gut microbiota in
shaping human health is well recognized. Studies have shown that gut microbiota is closely …

Over the last 50 years Dunedin Study researchers have published more than 1400 peer-
reviewed journal articles, books, and reports on many aspects of human health and …

The onset of schizophrenia is determined by biological and social risk factors operating
predominantly during development. These result in subtle deviations in brain structure and …

Survivors of childhood cancer may experience accelerated biological aging, resulting in
premature frailty and death. We used seven measures of biological age in the St. Jude …