Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

Age-associated chronic inflammation is characterized by unresolved and uncontrolled
inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …

Background The degree to which infection with SARS-CoV-2 confers protection towards
subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of …

Aging leads to numerous changes that affect all physiological systems of the body including
the immune system, causing greater susceptibility to infectious disease and contributing to …

As is apparent from the many contributions to this Special Issue of the Journal, the impact of
age on immunity is nefarious, with all manner of dysregulated responses attributed to …

Components of the innate immune response, including neutrophils and macrophages, are
the first line of defense against infections. Their role is to initiate an inflammatory response …

Ageing causes loss of function in tissues and organs, is accompanied by a chronic
inflammatory process and affects life‐and healthspan. Calorie restriction (CR) is a non …

Importance Due to the ongoing bacillus Calmette-Guérin (BCG) shortage, sequential
intravesical gemcitabine and docetaxel has been increasingly used as first-line therapy for …

The aging process is one of the best examples of the effects of a deterioration of
homeostasis, since aging is accompanied by an impairment of the physiological systems …

The treatment of inflammatory bowel disease (IBD) has been revolutionised over the past
decade by the increasing use of immunomodulators, mainly azathioprine (AZA)/6 …