Many parts of the animal body harbor microbial communities, known as animal-associated
microbiomes, that affect the regulation of physiological functions. Studies in human and …

Aging is the biggest risk factor for developing Parkinson's disease (PD), the second most
common neurodegenerative disorder. Several animal models have been developed to …

Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

The field of aging is at a precipice. Attention and funding are increasingly focused on this
area, and exciting, fundamentally important findings are being reported literally every day …

Research on aging and lifespan-extending compounds has been carried out using diverse
model organisms, including yeast, worms, flies and mice. Many studies reported the …

Aging is a natural phenomenon characterized by accumulation of cellular damage and
debris. Oxidative stress, cellular senescence, sustained inflammation, and DNA damage are …

Cellular senescence is a highly complicated cellular state that occurs throughout the
lifespan of an organism. It has been well-defined in mitotic cells by various senescent …

Background Anorexia of aging, defined as a decrease in appetite and a preponderant loss
of body weight occurring in late life, is one of the most common diseases affecting older …

In today's post-genomic era, it is crucial to rethink the concept of model organisms. While a
few historically well-established organisms, eg laboratory rodents, have enabled significant …

Ageing is the time-dependent gradual decline of the functional characteristics in an
organism. It has been shown that it results in the loss of reproductive health and fertility. The …