[HTML][HTML] Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

[HTML][HTML] Phosphorylated tau in Alzheimer's disease and other tauopathies

P Rawat, U Sehar, J Bisht, A Selman… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is the leading cause of dementia in elderly people. Amyloid beta
(Aβ) deposits and neurofibrillary tangles are the major pathological features in an …

[HTML][HTML] Neuroinflammation in Alzheimer's disease

IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

The promise of music therapy for Alzheimer's disease: a review

AM Matziorinis, S Koelsch - Annals of the New York Academy of …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with
cognitive decline. Memory problems are typically among the first signs of cognitive …

[HTML][HTML] NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic …

Y Zhao, J Zhang, Y Zheng, Y Zhang, XJ Zhang… - Journal of …, 2021 - Springer
Background Microglial-mediated neuroinflammation plays an important role in vascular
dementia, and modulating neuroinflammation has emerged as a promising treatment target …

Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: an update on current advances and …

MU Rehman, N Sehar, NJ Dar, A Khan, A Arafah… - Neuroscience & …, 2023 - Elsevier
Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia

G Zhong, H Long, T Zhou, Y Liu, J Zhao, J Han, X Yang… - Biomaterials, 2022 - Elsevier
Current treatments for Alzheimer's disease (AD) that focus on inhibition of Aβ aggregation
failed to show effectiveness in people who already had Alzheimer's symptoms. Strategies …

Oxidative stress in intervertebral disc degeneration: molecular mechanisms, pathogenesis and treatment

Y Wang, H Cheng, T Wang, K Zhang, Y Zhang… - Cell …, 2023 - Wiley Online Library
Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …

[HTML][HTML] Crosstalk between gut and brain in Alzheimer's disease: the role of gut microbiota modulation strategies

U Shabbir, MS Arshad, A Sameen, DH Oh - Nutrients, 2021 - mdpi.com
The gut microbiota (GM) represents a diverse and dynamic population of microorganisms
and about 100 trillion symbiotic microbial cells that dwell in the gastrointestinal tract. Studies …

[HTML][HTML] The role of microbiome in brain development and neurodegenerative diseases

V Nandwana, NK Nandwana, Y Das, M Saito, T Panda… - Molecules, 2022 - mdpi.com
Hundreds of billions of commensal microorganisms live in and on our bodies, most of which
colonize the gut shortly after birth and stay there for the rest of our lives. In animal models …