Natural bioactive products as promising therapeutics: A review of natural product-based drug development

CB Aware, DN Patil, SS Suryawanshi, PR Mali… - South African Journal of …, 2022 - Elsevier
Since ancient times, natural medicines have had paramount importance in bolstering
biotherapeutics to treat various diseases. The World Health Organization (WHO) revealed …

The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities

MAR Mia, D Dey, MR Sakib, MY Biswas… - Phytotherapy …, 2023 - Wiley Online Library
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Oxidative Stress and Natural Products in Orthodontic Treatment: A Systematic Review

F Inchingolo, AM Inchingolo, G Latini, L Ferrante, I Trilli… - Nutrients, 2023 - mdpi.com
In recent years, orthodontics, a specialized branch of dentistry, has evolved considerably in
terms of both techniques and materials used. Aimed at correcting dental malocclusions and …

Pharmacological, neurochemical, and behavioral mechanisms underlying the anxiolytic-and antidepressant-like effects of flavonoid chrysin

JF Rodríguez-Landa, LJ German-Ponciano… - Molecules, 2022 - mdpi.com
Chrysin (5, 7-dihydroxyflavone) is a flavonoid isolated from plants, such as Passiflora
coerulea, Passiflora incarnata, and Matricaria chamomilla. This natural molecule exerts …

Assessment of quercetin antiemetic properties: In vivo and in silico investigations on receptor binding affinity and synergistic effects

R Chowdhury, MS Bhuia, AI Rakib, R Hasan… - Plants, 2023 - mdpi.com
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has
demonstrated a diverse range of biological activities. The primary objective of the current …

Therapeutic potentials of ononin with mechanistic insights: A comprehensive review

MS Bhuia, MA Aktar, R Chowdhury, J Ferdous… - Food Bioscience, 2023 - Elsevier
Ononin is a naturally occurring isoflavone glycoside generally found in various plants like
soybeans, legumes, Chinese licorice, Mongolian milkvetch, kudzu, broccoli, and lupine. The …

Plant exosomal vesicles: perspective information nanocarriers in biomedicine

Y Shkryl, Z Tsydeneshieva, A Degtyarenko, Y Yugay… - Applied Sciences, 2022 - mdpi.com
Exosomal nanoparticles (exosomes or nanovesicles) are biogenic membrane vesicles
secreted by various cell types and represent a conservative mechanism of intercellular and …

New natural Eugenol derivatives as antiproliferative agents: synthesis, biological evaluation, and computational studies

S Nazreen, SEI Elbehairi, AM Malebari, N Alghamdi… - ACS …, 2023 - ACS Publications
Semisynthetic modifications of natural products have bestowed us with many anticancer
drugs. In the present work, a natural product, eugenol, has been modified synthetically to …

Determination of Chemical Compounds and Investigation of Biological Properties of Matricaria chamomilla Essential Oils, Honey, and Their Mixture

A Qasem, H Assaggaf, D Montesano, Z Khalil… - Molecules, 2022 - mdpi.com
This exploratory investigation aimed to determine the chemical composition and evaluate
some biological properties, such as antioxidant, anti-inflammatory, antidiabetic, and …

Composition and antibacterial, anti-inflammatory, antioxidant, and anticancer activities of Rosmarinus officinalis L. essential oil

E Becer, EM Altundağ, M Güran, HS Vatansever… - South African Journal of …, 2023 - Elsevier
Rosemary is a culinary herb that is widely used in traditional medicine for its nutritional value
and pharmacological properties. The aim of this study was to investigate the composition, in …