Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Organ-specific biological clocks: Ageotyping for personalized anti-aging medicine

F Prattichizzo, C Frigé, V Pellegrini, L Scisciola… - Ageing Research …, 2024 - Elsevier
Aging is a complex multidimensional, progressive remodeling process affecting multiple
organ systems. While many studies have focused on studying aging across multiple organs …

Ratio of Red Blood Cell Distribution Width to Albumin Level and Risk of Mortality

M Hao, S Jiang, J Tang, X Li, S Wang, Y Li… - JAMA Network …, 2024 - jamanetwork.com
Importance The ratio of red blood cell distribution width (RDW) to albumin concentration
(RAR) has emerged as a reliable prognostic marker for mortality in patients with various …

[PDF][PDF] Validation of biomarkers of aging

Biomarkers of Aging Consortium - Nature Medicine, 2024 - research.ed.ac.uk
Brain Development Network, Canadian Institute for Advanced Research and SocioMed
Research 87 Nucleus, Universidad Mayor, Santiago, Chile. DB is an inventor of …

MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data

C Boetto, A Frouin, L Henches… - Briefings in …, 2024 - academic.oup.com
Multivariate analysis is becoming central in studies investigating high-throughput molecular
data, yet, some important features of these data are seldom explored. Here, we present …

[HTML][HTML] Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks

K Yusri, S Kumar, S Fong, J Gruber… - International Journal of …, 2024 - mdpi.com
Aging is a complex and time-dependent decline in physiological function that affects most
organisms, leading to increased risk of age-related diseases. Investigating the molecular …

[PDF][PDF] Machine learning for human biological age estimation based on clinical blood analysis

VH Slipchenko, LH Poliahushko… - Applied Aspects of …, 2023 - dspace.op.edu.ua
This article explores the issue of estimating the biological age of a person using machine
learning techniques. Biological age is a statistical indicator that reflects the degree of aging …

Association of red cell distribution width to albumin ratio with risk of all-cause and cause-specific mortality: two prospective cohort studies

M Hao, S Jiang, X Li, S Wang, Y Li, J Tang, Z Hu… - medRxiv, 2024 - medrxiv.org
Background The red cell distribution width to albumin ratio (RAR) has emerged as a reliable
prognostic marker for mortality in various diseases. However, whether RAR is associated …