Innate and adaptive immunity to SARS-CoV-2 and predisposing factors

J Shen, J Fan, Y Zhao, D Jiang, Z Niu, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has affected all countries worldwide. Although some …

Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease

A Allué-Guardia, JB Torrelles, A Sigal - Frontiers in Immunology, 2023 - frontiersin.org
Mycobacterium tuberculosis (M. tb) and SARS-CoV-2 are both infections that can lead to
severe disease in the lower lung. However, these two infections are caused by very different …

Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection

SS Mahalingam, S Jayaraman, A Arunkumar… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus
Disease 2019 (COVID-19) that presents with varied clinical manifestations ranging from …

Prognostic significance of hypertension history and blood pressure on admission in Japanese patients with coronavirus disease 2019: integrative analysis from the …

K Sakurai, S Chubachi, T Asakura, H Namkoong… - Hypertension …, 2024 - nature.com
The effect of preexisting hypertension on coronavirus disease 2019 (COVID-19) prognosis
remains controversial. Additionally, no studies have compared the association between …

Anti-inflammatory effects of nutritionally relevant concentrations of oleuropein and hydroxytyrosol on peripheral blood mononuclear cells: an age-related analysis

F Pojero, F Gervasi, SD Fiore, A Aiello… - International Journal of …, 2023 - mdpi.com
Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The
Mediterranean diet is a non-invasive intervention to improve the chronic low-grade …

Children's SARS-CoV-2 infection and their vaccination

SL Gupta, R Tyagi, A Dhar, N Oswal, A Khandelwal… - Vaccines, 2023 - mdpi.com
SARS-CoV-2, a novel coronavirus, causes respiratory tract infections and other
complications in affected individuals, and has resulted in numerous deaths worldwide. The …

Baseline and early changes in laboratory parameters predict disease severity and fatal outcomes in COVID-19 patients

A Gize, Y Belete, M Kassa, W Tsegaye… - Frontiers in Public …, 2023 - frontiersin.org
Introduction Coronavirus disease 2019 (COVID-19) has become the worst catastrophe of the
twenty-first century and has led to the death of more than 6.9 million individuals across the …

Challenges in the Vaccination of the Elderly and Strategies for Improvement

G Soegiarto, D Purnomosari - Pathophysiology, 2023 - mdpi.com
In recent years, the elderly has become a rapidly growing proportion of the world's
population as life expectancy is extending. Immunosenescence and inflammaging …

Evaluation of hematological parameters alterations in different waves of COVID-19 pandemic: A cross-sectional study

J Charostad, M Rezaei Zadeh Rukerd, A Shahrokhi… - PloS one, 2023 - journals.plos.org
Background The occurrence of variations in routine hematological parameters is closely
associated with disease progression, the development of severe illness, and the mortality …

Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models

C Usai, E Ainsua-Enrich, VU Gales, E Pradenas… - npj Vaccines, 2024 - nature.com
Age is associated with reduced efficacy of vaccines and linked to higher risk of severe
COVID-19. Here we determined the impact of ageing on the efficacy of a SARS-CoV-2 …