A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

The numbers of potential neurotoxicants in the environment are raising and pose a great risk
for humans and the environment. Currently neurotoxicity assessment is mostly performed to …

Scientific evidence based on neuroimaging approaches over the last decade has
demonstrated the efficacy of physical activity improving cognitive health across the human …

Astrocytes metabolically interact with neighboring neurons by providing multiple substances
to neurons. How astrocytes regulate neural functions via altering the neuronal metabolic …

Dnmt1 and Dnmt3a are important DNA methyltransferases that are expressed in postmitotic
neurons, but their function in the CNS is unclear. We generated conditional mutant mice that …

Cellular memory is provided by two counteracting groups of chromatin proteins termed
Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate …

Maternal exposure to stress during pregnancy is associated with significant alterations in
offspring neurodevelopment and elevated maternal glucocorticoids likely play a central role …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor
neurons, which results in weakness and atrophy of voluntary skeletal muscles. Treatments …

We have evaluated the possibility that the action of voluntary exercise on the regulation of
brain‐derived neurotrophic factor (BDNF), a molecule important for rat hippocampal …

Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …