Biological clock technologies are designed to assess the acceleration of biological age (B-
age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to …

Epigenetic aging clocks are computational models that use DNA methylation sites to predict
age. Since cheek swabs are non-invasive and painless, collecting DNA from buccal tissue is …

Recent studies suggest that epigenetic rejuvenation can be achieved using drugs that mimic
calorie restriction and techniques such as reprogramming‐induced rejuvenation. To …

We present a systematic analysis of epigenetic age acceleration based on by far the largest
collection of publicly available DNA methylation data for healthy samples (93 datasets, 23 K …

Aging is one of the most intriguing processes of human ontogenesis. It is associated with the
development of a wide variety of diseases affecting all organs and their systems. The victory …

Aging of mice can be tracked by DNA methylation changes at specific sites in the genome. In
this study, we used the recently released Infinium Mouse Methylation BeadChip to compare …

Abstract Background and objectives The Developmental Origins of Health and Disease
hypothesis posits that early life adversity is associated with poor adult health outcomes …

The ability of T cells to undergo robust cell division in response to antigenic stimulation is
essential for competent T cell function. However, this ability is reduced with aging and …

Social inequalities in health relate to the systematic relationship that exists between
socioeconomic groups and a wide range of adverse health conditions and mortality both …

Abstract Evaluation of DNA methylation (DNAm) patterns is a promising tool for age
estimation. The duplex droplet digital PCR (ddPCR) method has been recently investigated …