Aging of mice can be tracked by DNA methylation changes at specific sites in the genome. In
this study, we used the recently released Infinium Mouse Methylation BeadChip to compare …

It is imperative to optimise health and healthspan across the lifespan. The accumulation of
reactive oxygen species (ROS) has been implicated in the hallmarks of ageing and …

Abstract Background and objectives The Developmental Origins of Health and Disease
hypothesis posits that early life adversity is associated with poor adult health outcomes …

The ability of T cells to undergo robust cell division in response to antigenic stimulation is
essential for competent T cell function. However, this ability is reduced with aging and …

Social inequalities in health relate to the systematic relationship that exists between
socioeconomic groups and a wide range of adverse health conditions and mortality both …

Abstract Evaluation of DNA methylation (DNAm) patterns is a promising tool for age
estimation. The duplex droplet digital PCR (ddPCR) method has been recently investigated …

Epigenetic age estimation has the potential to influence conservation approaches for
wildlife. DNA extracted from a small skin sample can be analyzed for methylation changes …

As a link between a stable genome and a dynamic environment, epigenetics is a promising
tool for mapping age-related changes in human DNA. Methylated cytosine changes at …

In recent years there has been a widespread interest in researching biomarkers of aging that
could predict physiological vulnerability better than chronological age. Aging, in fact, is one …

For almost a century, telomeres have been increasingly studied in biological and biomedical
sciences with the ultimate hope that changes in telomere DNA length (abbreviated as TL) …