Der Einfluss von klonaler Hämatopoese unbekannten Potentials auf die epigenetische Altersbeschleunigung

JD Feldkamp - 2023 - refubium.fu-berlin.de
Das Phänomen der klonalen Hämatopoese von unbekanntem Potenzial (clonal hema-
topoiesis of indeterminate potential, CHIP) betrifft einen erheblichen Teil der älteren …

Epigenetic signatures of developmental psychopathology: time-varying associations of general psychopathology across childhood and adolescence with late …

L Separovic - 2023 - open.library.ubc.ca
Psychopathology is known to fluctuate throughout childhood and adolescence, in
association with a variety of intrinsic (eg, genetic) and extrinsic (eg, environmental) factors …

Causality between ageing and 24 gastrointestinal diseases: a bidirectional Mendelian randomization study

Y Ren, L He, H Li - 2024 - researchsquare.com
Purpose The relationship between aging and gastrointestinal diseases has not been
extensively studied. This study aims to investigate the correlation between various proxies of …

THE ASSOCIATION OF PRENATAL AMBIENT AIR POLLUTION WITH PLACENTAL EPIGENETIC GESTATIONAL AGE AT BIRTH

Z He - 2023 - jscholarship.library.jhu.edu
Background: Prenatal exposure to air pollution (AP) is a well-established risk factor for
adverse birth outcomes, yet mechanisms remain inconclusive. Changes to placenta DNA …

Recalibrating the cerebellum DNA methylation clock: implications for ageing rates comparison

Y Wang, OA Grant, X Zhai, KD McDonald-Maier… - bioRxiv, 2022 - biorxiv.org
Background DNA methylation (DNAm) based age clocks have been studied extensively as a
biomarker of human ageing and risk factor for age-related diseases. Despite different tissues …

IF1 Protein Controls Aging Rate

MD Forrest - bioRxiv, 2021 - biorxiv.org
ABSTRACT IF1 protein inhibits F1F0 ATP hydrolysis (and not F1F0 ATP synthesis). Across
investigated species more IF1 protein, and less F1F0 ATP hydrolysis, correlates with greater …

Investigating Pace of Biological Aging as a Mental and Physical Health Biomarker in Youth with Perinatally-Acquired HIV

H Chang - 2023 - search.proquest.com
HIV and its treatment may affect the growth and development of organ function and the
mental health of youth who are living with perinatally-acquired HIV (PHIV). Recent research …

The influence of biological and statistical properties of CpGs on epigenetic predictions of eighteen traits

RF Hillary, DL McCartney, AF McRae, A Campbell… - bioRxiv, 2022 - biorxiv.org
Background CpG methylation levels can help to explain inter-individual differences in
phenotypic traits. Few studies have explored whether identifying CpG subsets based on …

Metabolic predictors of phenotypic traits can replace and complement measured clinical variables in transcriptome-wide association studies

A Niehues, D Bizzarri, MJT Reinders, PE Slagboom… - bioRxiv, 2022 - biorxiv.org
Transcriptome-wide association studies (TWAS) can provide valuable insights into
biological and disease-underlying mechanisms. For studying clinical effects, availability of …

Epigenetic aging and its reversal

C de la Parte, D Guallar - Molecular, Cellular, and Metabolic …, 2022 - books.google.com
Epigenetics refers to all of the molecular mechanisms involved in gene expression
regulation that can be inherited and do not involve changes in the sequence of DNA itself …