The accumulation of senescent cells within tissues is a hallmark of the aging process.
Senescent cells are also commonly present in many age-related diseases and in the cancer …

Aging and cancer exhibit apparent links that we will examine in this review. The null
hypothesis that aging and cancer coincide because both are driven by time, irrespective of …

Ulcerative colitis (UC) is a subtype of inflammatory bowel disease. Previous studies have
suggested a link between senescence process and the body's inflammatory reaction …

Nicotinamide adenine dinucleotide (NAD+) plays a crucial role in the cellular energy
metabolism pathway. Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting …

Cellular senescence (CS) is recognized as one of the hallmarks of aging, and an important
player in a variety of age-related pathologies. Accumulation of senescent cells can promote …

Aging, a complex biological process influenced by genetic, environmental, and
pharmacological factors, presents a significant challenge in understanding its underlying …

Recently, DNA methylation clocks have been proven to be precise age predictors, and the
application of these clocks in cancer tissue has revealed a global age acceleration in a …

The intertwined ageing, the extracellular matrix, and fibrosis Page 1 1 The intertwined ageing,
the extracellular matrix, and fibrosis 1 Alexander Nyström1 2 1Department of Dermatology …

Background: Alzheimer's disease (AD) is an age-related neurodegenerative disease that is
clinically characterized by progressive cognitive decline. Glucagon-like peptide-1 (GLP-1) is …

The mechanistic target of rapamycin (mTOR) positively regulates multiple steps of the HIV-1
replication cycle. We previously reported that a 12-weeks supplementation of antiretroviral …