The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

To build health equity for an aging world marked by dramatic disparities in healthy lifespan
between countries, regions and population groups, research at the intersections of biology …

Over the past 2 decades, population simulation modeling has evolved as an effective public
health tool for surveillance of cancer trends and estimation of the impact of screening and …

Geroscience posits that cardiovascular disease (CVD) and other chronic diseases result
from progressive erosion of the effectiveness of homeostatic mechanisms that oppose age …

Importance The Dunedin Pace of Aging Calculated From the Epigenome (DunedinPACE)
measure is a newly constructed DNA methylation (DNAm) biomarker associated with …

Cardiovascular ageing is a process that begins early in life and leads to a progressive
change in structure and decline in function due to accumulated damage across diverse cell …

Background Frailty, a clinical syndrome commencing at midlife, is a risk for morbidity and
mortality. Little is known about the factors that contribute to the chronic inflammatory state …

BackgroundThe current study examined if early adversity was associated with accelerated
biological aging, and if effects were mediated by the timing of puberty. MethodsIn early mid …

ABSTRACT The American Society for Transplantation and Cellular Therapy (ASTCT) and
the National Marrow Donor Program (NMDP) have formed the ACCESS Initiative to address …