H Haase, L Rink - Immunity & Ageing, 2009 - Springer
The trace element zinc is essential for the immune system, and zinc deficiency affects multiple aspects of innate and adaptive immunity. There are remarkable parallels in the …
A Salminen - Journal of Molecular Medicine, 2021 - Springer
The functional competence of the immune system gradually declines with aging, a process called immunosenescence. The age-related remodelling of the immune system affects both …
DP Shanley, D Aw, NR Manley, DB Palmer - Trends in immunology, 2009 - cell.com
There is an accumulating body of evidence that a decline in immune function with age is common to most if not all vertebrates. For instance, age-associated thymic involution seems …
A Salminen, K Kaarniranta, A Kauppinen - Cellular and Molecular Life …, 2019 - Springer
The aging process is associated with chronic low-grade inflammation in both humans and rodents, commonly called inflammaging. At the same time, there is a gradual decline in the …
The diet in the elderly does not provide a sufficient level of nutrients needed to maintain an adequate healthy status leading to micronutrient deficiencies and impaired immune …
F Borrego, MC Alonso, MD Galiani, J Carracedo… - Experimental …, 1999 - Elsevier
Immunosenescence is a process that primarily affects the T cell compartment of the immune system, although age-associated immunological alterations have also been demonstrated in …
N Drela, E Kozdron, P Szczypiorski - BMC geriatrics, 2004 - Springer
Background Immunosenescence is related to the deterioration of many immune functions, which may be manifested in increased susceptibility to infection, cancer, and autoimmunity …
A Salminen, K Kaarniranta, A Kauppinen - Ageing research reviews, 2018 - Elsevier
A chronic low-grade inflammation is one of the hallmarks of the aging process. This gradually augmenting inflammatory state has been termed inflammaging. Inflammaging is …
L Zhao, L Sun, H Wang, H Ma, G Liu… - Journal of Leucocyte …, 2007 - academic.oup.com
A progressive decline in the integrity of the immune system is one of the physiologic changes during aging. The frequency of autoimmune diseases or immune disorders …