Despite the depth of knowledge concerning the pathogenesis of acute myeloblastic
leukemia (AML), long-term survival remains unresolved. Therefore, new agents that act …

3-Hydrogenkwadaphnin (3-HK) is a daphnane-type diterpene ester isolated from
Dendrostellera lessertii (Thymelaeaceae) with high differentiation and apoptotic potency in …

Chronic myeloid leukemia (CML) is a hematological malignancy that arises due to reciprocal
translocation of 3′ sequences from c-Abelson (abl) protooncogene on chromosome 9 with …

Leukemia remains a major cause of death in both developing as well as developed nations
worldwide. Development of novel therapeutic approaches is perceived to be the best …

Recently, we have reported that 3-hydrogenkwadaphnin (3-HK), a diterpene ester isolated
from Dendrostellera lessertii (Thymealeaceae), is very effective against leukemia cell lines …

3-Hydrogenkwadaphnin (3-HK)(Fig. 1) is a daphnane-type diterpene ester isolated from the
leaves of Dendrostellera lessertii (Thymelaeaceae) with differentiation and apoptotic …

Background and purpose: Royal jelly (RJ) is a substance synthesized by worker bee-is
shown to have various biological activities on different cells and tissues of the human body …

Background: Regarding the strong differentiation and anti-leukemic activity of
Dendrostellera lessertii extract, an active agent with similar capabilities was isolated from …

Background & Aims: Leukemia is a particular type of cancer characterized by the failure of
cell death or disability in the differentiation of hematopoietic cells. Chronic myelogenous …