Regulation of NAD+ metabolism in aging and disease

X Chu, RP Raju - Metabolism, 2022 - Elsevier
More than a century after discovering NAD+, information is still evolving on the role of this
molecule in health and diseases. The biological functions of NAD+ and NAD+ precursors …

Mitochondrial dysfunction and Parkinson's disease: pathogenesis and therapeutic strategies

S Moradi Vastegani, A Nasrolahi, S Ghaderi… - Neurochemical …, 2023 - Springer
Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

[HTML][HTML] Targeting metabolic reprogramming in chronic lymphocytic leukemia

Y Nie, X Yun, Y Zhang, X Wang - Experimental Hematology & Oncology, 2022 - Springer
Metabolic reprogramming, fundamentally pivotal in carcinogenesis and progression of
cancer, is considered as a promising therapeutic target against tumors. In chronic …

Uncovering novel disinfection mechanisms of solar light/periodate system: The dominance of singlet oxygen and metabolomic insights

C Ye, K Zhang, X Wu, K Wan, WF Cai, M Feng… - Journal of Hazardous …, 2023 - Elsevier
Disinfection plays an essential role in waterborne pathogen control and disease prevention,
especially during the COVID-19 pandemic. Catalyst-free solar light/periodate (PI) system …

The tricarboxylic acid (TCA) cycle: a malleable metabolic network to counter cellular stress

A MacLean, F Legendre… - Critical Reviews in …, 2023 - Taylor & Francis
The tricarboxylic acid (TCA) cycle is a primordial metabolic pathway that is conserved from
bacteria to humans. Although this network is often viewed primarily as an energy producing …

[HTML][HTML] Lycopene maintains mitochondrial homeostasis to counteract the enterotoxicity of deoxynivalenol

Z Cai, F Chen, Y Wang, X Wang, X Yang, C Zhang - Antioxidants, 2023 - mdpi.com
The intestinal tract is a target organ for Deoxynivalenol (DON) absorption and toxicity.
Mitochondrial homeostasis imbalance is the gut toxicity mechanism of DON. Lycopene …

[HTML][HTML] Can the mitochondrial metabolic theory explain better the origin and management of cancer than can the somatic mutation theory?

TN Seyfried, C Chinopoulos - Metabolites, 2021 - mdpi.com
A theory that can best explain the facts of a phenomenon is more likely to advance
knowledge than a theory that is less able to explain the facts. Cancer is generally …

[HTML][HTML] Efficacy of probiotics on the modulation of gut microbiota in the treatment of diabetic nephropathy

N Nagase, Y Ikeda, A Tsuji, Y Kitagishi… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is a major cause of end-stage renal disease, and therapeutic
options for preventing its progression are insufficient. The number of patients with DN has …

Reshaping fish intestinal microbiota and facilitating barrier function by ZnO nanoparticles

S Ma, WX Wang - Environmental Science: Nano, 2023 - pubs.rsc.org
Nano-Zn (nZnO) has been increasingly applied in different fields, but the mechanisms of
their uses as nutritional sources are less understood. Our study presents a regulatory …

[HTML][HTML] Comparative omics analysis of a new deep-sea barnacle species (Cirripedia, Scalpellomorpha) and shallow-water barnacle species provides insights into …

N Mao, W Shao, Y Cai, X Kong, N Ji… - Frontiers in Marine …, 2024 - frontiersin.org
Barnacles have demonstrated adaptability to a range of habitats, spanning from shallow
water to the deep sea. Given the harsh conditions present in hydrothermal vents …