Stressful life experiences are associated with the development of neuropsychiatric disorders like depression. Emerging evidence indicates that microglia, the specialized resident …
In humans, exposure to early life stress (ELS) is an established risk factor for the development of substance use disorders (SUDs) during later life. Similarly, rodents exposed …
SM Loewen, AM Chavesa, CJ Murray, ME Traetta… - 2023 - karger.com
Maternal immune activation (MIA) can result from a variety of maternal inflammatory factors, including metabolic disorders, nutritional deficits, infections, and psychosocial stress. MIA …
R Ramkumar, M Edge-Partington, DJ Terstege… - Biological …, 2024 - Elsevier
Background Chronic childhood stress is a prominent risk factor for developing affective disorders, yet mechanisms underlying this association remain unclear. Maintenance of …
Abnormal development and function of the hippocampus are two of the most consistent findings in humans and rodents exposed to early life adversity, with males often being more …
M Lamar, KN Kershaw, SE Leurgans… - Frontiers in Human …, 2023 - frontiersin.org
Introduction Despite known health disparities in cognitive aging, a comprehensive rationale for the increased burden in older minoritized populations including non-Latino Black and …
JA Sheng, SA Tobet - Journal of Neuroendocrinology, 2024 - Wiley Online Library
Infections during pregnancy are associated with increased risk for adult neuropsychiatric disease, such as major depressive disorder, schizophrenia, and autism spectrum disorder …
M Rincón-Cortés - Addiction, 2023 - researchgate.net
abstract In humans, exposure to early life stress (ELS) is an established risk factor for the development of substance use disorders (SUDs) during later life. Similarly, rodents exposed …
Neuropsychiatric disorders encompass a wide range of conditions that affect neurological health and brain function and lead to disabilities worldwide. Such disorders include, but are …