[HTML][HTML] MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets

S Liu, M Fan, Q Zheng, S Hao, L Yang, Q Xia… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease, with cognitive
decline as the primary clinical feature. According to epidemiological statistics, 50 million …

Current state of Alzheimer's fluid biomarkers

JL Molinuevo, S Ayton, R Batrla, MM Bednar… - Acta …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

[HTML][HTML] Relationship between amyloid-β deposition and blood–brain barrier dysfunction in Alzheimer's disease

D Wang, F Chen, Z Han, Z Yin, X Ge… - Frontiers in Cellular …, 2021 - frontiersin.org
Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …

Anthocyanins and human health—a focus on oxidative stress, inflammation and disease

H Speer, NM D'Cunha, NI Alexopoulos, AJ McKune… - Antioxidants, 2020 - mdpi.com
Consumption of anthocyanins (ACNs), due to their antioxidant, anti-inflammatory and anti-
apoptotic effects, has been proposed for the prevention and treatment of several different …

Alzheimer's disease pharmacotherapy in relation to cholinergic system involvement

GD Stanciu, A Luca, RN Rusu, V Bild… - Biomolecules, 2019 - mdpi.com
Alzheimer's disease, a major and increasing global health challenge, is an irreversible,
progressive form of dementia, associated with an ongoing decline of brain functioning. The …

[HTML][HTML] Mitochondrial dysfunction and Alzheimer's disease: Role of microglia

I Agrawal, S Jha - Frontiers in aging neuroscience, 2020 - frontiersin.org
In 1907 Alois Alzheimer observed, as he quoted, development of “numerous fibers” and
“adipose saccules” in the brain of his diseased patient Auguste Deter. The …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

[HTML][HTML] A molecular approach in drug development for Alzheimer's disease

S Agatonovic-Kustrin, C Kettle, DW Morton - Biomedicine & …, 2018 - Elsevier
An increase in dementia numbers and global trends in population aging across the world
prompts the need for new medications to treat the complex biological dysfunctions, such as …

Neurodegenerative diseases: Regenerative mechanisms and novel therapeutic approaches

R Hussain, H Zubair, S Pursell, M Shahab - Brain sciences, 2018 - mdpi.com
Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …

Exercise interventions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials

S Lopez-Ortiz, PL Valenzuela, MM Seisdedos… - Ageing Research …, 2021 - Elsevier
Aims To assess the potential multi-domain benefits of exercise interventions on patients with
Alzheimer's disease (AD), as well as to determine the specific effects of different exercise …