In concert with neuropeptides and transmitters, the end products of the hypothalamus-
pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone …

Obesity is a major health risk, with junk food consumption playing a central role in weight
gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet …

Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

Early-life stress (ELS) is associated with increased vulnerability to mental disorders. The
basolateral amygdala (BLA) plays a critical role in fear conditioning and is extremely …

Addiction is a chronic relapsing disorder with devastating personal, societal, and economic
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …

Low statistical power reduces the reliability of animal research; yet, increasing sample sizes
to increase statistical power is problematic for both ethical and practical reasons. We present …

Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including
depression later in life. Neuroinflammatory processes have been implicated in ELS-induced …

In the biomedical, behavioral and neurobiological sciences reproducibility and replicability
of research results have become a major issue. The question is whether attachment …

Exposure to early-life adversity (ELA) increases the risk for psychopathologies associated
with amygdala-prefrontal cortex (PFC) circuits. While sex differences in vulnerability have …

Although early life stress (ELS) can increase susceptibility to adulthood psychiatric disorders
and produce a greater inflammatory response in a stressful event, targeted preventive and …