[HTML][HTML] Reversing the immune ageing clock: lifestyle modifications and pharmacological interventions
NA Duggal - Biogerontology, 2018 - Springer
It is widely accepted that ageing is accompanied by remodelling of the immune system,
including reduced numbers of naïve T cells, increased senescent or exhausted T cells …
including reduced numbers of naïve T cells, increased senescent or exhausted T cells …
[HTML][HTML] Implication of the emergence of the delta (B. 1.617. 2) variants on vaccine effectiveness
Introduction COVID-19 vaccines have been developed to compact the current SARS-CoV-2
pandemic and have been administered to people all over the world. These vaccines have …
pandemic and have been administered to people all over the world. These vaccines have …
[HTML][HTML] SARS-CoV-2 vaccine safety and immunogenicity in patients with hematologic malignancies, transplantation, and cellular therapies
Individuals with hematological malignancies and hematopoietic stem cell transplant (HCT)
recipients are immunologically heterogenous groups with varying degrees of …
recipients are immunologically heterogenous groups with varying degrees of …
[HTML][HTML] Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection
L Demuth, M Ohm, K Michaelsen-Preusse… - Frontiers in …, 2023 - frontiersin.org
Influenza A virus (IAV) subtypes are a major cause of illness and mortality worldwide and
pose a threat to human health. Although IAV infection is considered a self-limiting respiratory …
pose a threat to human health. Although IAV infection is considered a self-limiting respiratory …
[HTML][HTML] Telomere shortening, inflammatory cytokines, and anti-cytomegalovirus antibody follow distinct age-associated trajectories in humans
A Lustig, HB Liu, EJ Metter, Y An, MA Swaby… - Frontiers in …, 2017 - frontiersin.org
A number of biological parameters have been cited as hallmarks of immune aging.
However, it is not clear whether these multiple biological changes are the result of common …
However, it is not clear whether these multiple biological changes are the result of common …
[HTML][HTML] Changes in circadian rhythms dysregulate inflammation in ageing: focus on leukocyte trafficking
P Nathan, JE Gibbs, GE Rainger… - Frontiers in immunology, 2021 - frontiersin.org
Leukocyte trafficking shows strong diurnal rhythmicity and is tightly regulated by circadian
rhythms. As we age, leukocyte trafficking becomes dysregulated, contributing to the …
rhythms. As we age, leukocyte trafficking becomes dysregulated, contributing to the …
Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15
DB Bartlett, NA Duggal - Age and ageing, 2020 - academic.oup.com
Introduction ageing is accompanied by impairments in immune responses due to
remodelling of the immune system (immunesenescence). Additionally, a decline in habitual …
remodelling of the immune system (immunesenescence). Additionally, a decline in habitual …
[HTML][HTML] Factors associated with the decay of anti-SARS-CoV-2 S1 IgG antibodies among recipients of an adenoviral vector-based AZD1222 and a whole-virion …
ST Selvavinayagam, YK Yong, HY Tan, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The magnitude of protection conferred following recovery from COVID-19 or by
vaccine administration, and the duration of protective immunity developed, remains …
vaccine administration, and the duration of protective immunity developed, remains …
[HTML][HTML] Effects of exercise and physical activity levels on vaccination efficacy: a systematic review and meta-analysis
Objective: We examined whether different intensities of exercise and/or physical activity (PA)
levels affected and/or associated with vaccination efficacy. Methods: A systematic review …
levels affected and/or associated with vaccination efficacy. Methods: A systematic review …