Over time, the human DNA methylation landscape accrues substantial damage, which has
been associated with a broad range of age-related diseases, including cardiovascular …

Despite impressive efforts invested in epigenetic research in the last 50 years, clinical
applications are still lacking. Only a few university hospital centers currently use epigenetic …

Epigenetic aging biomarkers are associated with increased morbidity and mortality. We
evaluated if occupational exposure to three established chemical carcinogens is associated …

Scope Obesity and insulin resistance (IR) are associated with epigenetic changes of gene
expression. However, the relationship between micronutrients, epigenetic regulation of gene …

Ageing is characterised by a physical decline in biological functioning which results in a
progressive risk of mortality with time. As a biological phenomenon, it is underpinned by the …

The rate of aging has increased globally during recent decades and has led to a rising
burden of age-related diseases such as cardiovascular disease (CVD). At the molecular …

Recent scientific evidence has shown the importance of diet and lifestyle habits for the
proper functioning of the human body. A balanced and healthy diet, physical activity, and …

Nephrolithiasis is an increasingly prevalent condition, especially in high income countries,
and is associated with high morbidity. Extraordinary progress in genetics made the …

Following a request from the European Commission (EC), the EFSA Panel on Nutrition,
Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the …

Background The interaction between genetic, epigenetic and environmental factors plays an
important role in the aetiology of hypertension. GWAS and observational studies link the …