The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …

Telomere shortening, a marker of cellular aging, has been linked to hospitalization and the
severity of COVID-19. In this systematic review and meta-analysis, the mean difference in …

Aims Heart failure (HF) is a prevalent age‐related cardiovascular disease with poor
prognosis in the elderly population. This study aimed to establish the causal relationship …

Background Aging has been reported as a major risk factor for severe symptoms and higher
mortality rates in COVID-19 patients. Molecular hallmarks such as epigenetic alterations and …

Background: Pathogenesis, diagnosis, and treatment of irritable bowel syndrome (IBS) have
been reported to be challenging hotspots in clinical practice. Previous observational studies …

The global impact of the SARS-CoV-2 pandemic has been unprecedented, posing a
significant public health challenge. Chronological age has been identified as a key …

It has been four years since long COVID—the protracted consequences that survivors of
COVID-19 face—was first described. Yet, this entity continues to devastate the quality of life …

Background The mortality rate of sepsis-associated liver injury (SALI) is relatively high, but
there is currently no authoritative prognostic criterion for the outcome of SALI. Meanwhile …

Introduction It has been suggested that type 1 diabetes was associated with increased
COVID-19 morbidity and mortality. However, their causal relationship is still unclear. Herein …

BACKGROUND: Epigenetic modifications may contribute to inter-individual variation that is
unexplainable by presently known risk factors for COVID-19 severity (eg, age, excess …