NF-κB signaling is essential to an effective innate and adaptive immune response. Many
immune-specific functional and developmental outcomes depend in large on NF-κB. The …

Abstract Chitinase‐3‐like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its
ability to regulate multiple biological processes, such as the inflammatory response and …

Individual cells are basic units of life. Despite extensive efforts to characterize the cellular
heterogeneity of different organisms, cross-species comparisons of landscape dynamics …

Single-cell RNA sequencing (scRNA-seq) is a powerful approach for studying cellular
differentiation, but accurately tracking cell fate transitions can be challenging, especially in …

Cardiogenesis is a tightly regulated dynamic process through a continuum of differentiation
and proliferation events. Key factors and pathways governing this process remain …

The liver is the main gateway from the gut, and the unidirectional sinusoidal flow from portal
to central veins constitutes heterogenous zones, including the periportal vein (PV) and the …

Commitment to specific cell lineages is critical for mammalian embryonic development.
Lineage determination, differentiation, maintenance, and organogenesis result in diverse life …

Building dynamic biological networks, especially DNA circuits, has provided a powerful
prospect for exploring the intrinsic regulation processes of live cells. Nevertheless, for …

Simple Summary Studies have shown that SPP1 plays an important role in the progression
of certain tumors, but the specific functional mechanism in gastric cancer (GC) is still unclear …

Venezuelan equine encephalitis virus (VEEV) is an encephalitic alphavirus responsible for
epidemics of neurological disease across the Americas. Low-density lipoprotein receptor …