Abstract Background The Wnt/β-catenin signaling pathway is critical in kidney development,
yet its specific effects on gene expression in different embryonic kidney cell types are not …

Extracts from Drosophila preblastoderm embryos (DREX) form the basis of a powerful in
vitro chromatin reconstitution system that assembles entire genomes into complex chromatin …

The mammalian Pre‐B cell leukaemia transcription factors 1–4 (PBX1‐4) constitutes the
PBC class of the homeodomain (HD)‐containing proteins, which play important roles in …

The aging process is a complex and multifaceted phenomenon affecting all living
organisms. It involves a gradual deterioration of tissue and cellular function, leading to a …

Odontoblast differentiation depends on the orderly recruitment of transcriptional factors (TFs)
in the transcriptional regulatory network. The depletion of crucial TFs disturbs dynamic …

Background: Type VI secretion system (T6SS) is widely present in Gram-negative bacteria
and directly mediates antagonistic prokaryote interactions. PAAR (proline-alanine-alanine …

Background: Differentiation of mouse stem cells (mESC) to embryonic bodies (EBs) is a
widely used approach to model early stages of development. In this study, we employed …

Single-cell and spatial transcriptomics have been widely used to characterize cellular
landscape in complex tissues. To understand cellular heterogeneity, one essential step is to …

Objective Despite intensive research on rheumatoid arthritis, the pathomechanism of the
disease is still not fully understood and the treatment has not been completely resolved …

Introduction Given the important roles of immune tolerance and inflammation in both preterm
and term labor, some inflammation-related genes could be related to the initiation of labor …