Background Cuproptosis is a newly discovered unique non-apoptotic programmed cell
death distinguished from known death mechanisms like ferroptosis, pyroptosis, and …

Tumor-associated macrophages (TAMs) are important immune cells in the tumor
microenvironment, and their invasion in tumors is closely related to poor prognosis …

Lower-grade glioma (LGG) is a group of tumors arising from the cells of the central nervous
system. Although various therapy interventions are used, the prognosis remains different …

Single-cell RNA sequencing (scRNA-seq) is an emerging technology used for cellular
transcriptome analysis. The application of scRNA-seq has led to profoundly advanced …

Background and aim: Ever since the discovery of tumor-associated immune cells, there has
been growing interest in the understanding of the mechanisms underlying the crosstalk …

Colorectal cancer (CRC) is one of the most lethal cancers. Single-cell RNA sequencing
(scRNA-seq) and protein-protein interactions (PPIs) have enabled the systematic study of …

Based on preclinical findings, programmed death-ligand 1 (PD-L1) can substantially
attenuate CD8+ T-cell-mediated anti-tumoral immune responses. However, clinical studies …

Background Lower-grade glioma (LGG) is a primary intracranial tumor that carry a high risk
of malignant transformation and limited therapeutic options. Emerging evidence indicates …

Background: Glioma is one of the major health problems worldwide. Biomarkers for
predicting the prognosis of Glioma are still needed. Methods: The transcriptome data and …

Objective The alternative extension of the telomeres (ALT) mechanism is activated in lower
grade glioma (LGG), but the role of the ALT mechanism has not been well discussed. The …