Adaptive immune responses and immunity to SARS-CoV-2

D Primorac, K Vrdoljak, P Brlek, E Pavelić… - Frontiers in …, 2022 - frontiersin.org
Since the onset of the COVID-19 pandemic, the medical field has been forced to apply the
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

R Vikkurthi, A Ansari, AR Pai, SN Jha, S Sachan… - Nature …, 2022 - nature.com
BBV152 is a whole-virion inactivated vaccine based on the Asp614Gly variant. BBV152 is
the first alum-imidazoquinolin-adjuvanted vaccine authorized for use in large populations …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

Assessment of humoral and cellular immunity induced by the BNT162b2 SARS-CoV-2 vaccine in healthcare workers, elderly people, and immunosuppressed patients …

G Malipiero, A Moratto, M Infantino, P D'Agaro… - Immunologic …, 2021 - Springer
The development of vaccines to prevent SARS-CoV-2 infection has mainly relied on the
induction of neutralizing antibodies (nAbs) to the Spike protein of SARS-CoV-2, but there is …

Dominant CD8+ T Cell Nucleocapsid Targeting in SARS-CoV-2 Infection and Broad Spike Targeting From Vaccination

E Taus, C Hofmann, FJ Ibarrondo, MA Hausner… - Frontiers in …, 2022 - frontiersin.org
CD8+ T cells have key protective roles in many viral infections. While an overall Th1-biased
cellular immune response against SARS-CoV-2 has been demonstrated, most reports of anti …

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

A Tomic, DT Skelly, A Ogbe, D O'Connor… - Nature …, 2022 - nature.com
The trajectories of acquired immunity to severe acute respiratory syndrome coronavirus 2
infection are not fully understood. We present a detailed longitudinal cohort study of UK …

Reduced T cell and antibody responses to inactivated coronavirus vaccine among individuals above 55 years old

GX Medeiros, GL Sasahara, JY Magawa… - Frontiers in …, 2022 - frontiersin.org
CoronaVac is an inactivated SARS-CoV-2 vaccine that has been rolled out in several low
and middle-income countries including Brazil, where it was the mainstay of the first wave of …

[HTML][HTML] Immunogenicity of an adjuvanted SARS-CoV-2 trimeric S-protein subunit vaccine (SCB-2019) in SARS-CoV-2-naïve and exposed individuals in a phase 2/3 …

E Buntinx, L Brochado, C Borja-Tabora, YY Charles… - Vaccine, 2023 - Elsevier
Background We evaluated immunogenicity of SCB-2019, a subunit vaccine candidate
containing a pre-fusion trimeric form of the SARS-CoV-2 spike (S)-protein adjuvanted with …