[HTML][HTML] Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

GD de Melo, V Perraud, F Alvarez… - Nature …, 2023 - nature.com
Anosmia was identified as a hallmark of COVID-19 early in the pandemic, however, with the
emergence of variants of concern, the clinical profile induced by SARS-CoV-2 infection has …

COVID-19 and psychosis risk: real or delusional concern?

CJ Watson, RH Thomas, T Solomon, BD Michael… - Neuroscience …, 2021 - Elsevier
Historical epidemiological perspectives from past pandemics and recent neurobiological
evidence link infections and psychoses, leading to concerns that COVID-19 will present a …

[HTML][HTML] CNS implications of COVID-19: a comprehensive review

P Nagu, A Parashar, T Behl, V Mehta - Reviews in the Neurosciences, 2021 - degruyter.com
Ms. Priyanka Nagu is a M. Pharm in Pharmaceutics and is currently pursuing her PhD in
neuroscience. Her area of interest includes the understanding of the pathogenesis and …

Blood–brain barrier injury and neuroinflammation induced by SARS-CoV-2 in a lung–brain microphysiological system

P Wang, L Jin, M Zhang, Y Wu, Z Duan, Y Guo… - Nature Biomedical …, 2023 - nature.com
In some patients, COVID-19 can trigger neurological symptoms with unclear pathogenesis.
Here we describe a microphysiological system integrating alveolus and blood–brain barrier …

[HTML][HTML] Neuroinflammation and Its Impact on the Pathogenesis of COVID-19

MM Almutairi, F Sivandzade, TH Albekairi… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical manifestations of COVID-19 …

[HTML][HTML] SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

P Mesci, JS de Souza, L Martin-Sancho, A Macia… - PLoS …, 2022 - journals.plos.org
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …

[HTML][HTML] SARS-CoV-2 promotes microglial synapse elimination in human brain organoids

n Samudyata, AO Oliveira, S Malwade… - Molecular …, 2022 - nature.com
Neuropsychiatric manifestations are common in both the acute and post-acute phase of
SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly …

[HTML][HTML] Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2

J Youk, T Kim, KV Evans, YI Jeong, Y Hur, SP Hong… - Cell Stem Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a
present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing …

[HTML][HTML] Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic interventions

Y Han, K Yuan, Z Wang, WJ Liu, ZA Lu, L Liu… - Translational …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused large-scale
economic and social losses and worldwide deaths. Although most COVID-19 patients have …

[HTML][HTML] Choosing a cellular model to study SARS-CoV-2

GA Pires De Souza, M Le Bideau, C Boschi… - Frontiers in cellular …, 2022 - frontiersin.org
As new pathogens emerge, new challenges must be faced. This is no different in infectious
disease research, where identifying the best tools available in laboratories to conduct an …