In vitro and in vivo models for studying SARS-CoV-2, the etiological agent responsible for COVID-19 pandemic
RB Rosa, WM Dantas, JCF do Nascimento… - Viruses, 2021 - mdpi.com
The emergence and rapid worldwide spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has prompted the scientific community to rapidly develop in …
coronavirus 2 (SARS-CoV-2) has prompted the scientific community to rapidly develop in …
Chronological brain lesions after SARS-CoV-2 infection in hACE2-transgenic mice
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes respiratory
disease, but it can also affect other organs including the central nervous system. Several …
disease, but it can also affect other organs including the central nervous system. Several …
[HTML][HTML] Neuropsychological functioning in post-ICU patients after severe COVID-19 infection: the role of cognitive reserve
A Costas-Carrera, MM Sánchez-Rodríguez… - Brain, Behavior, & …, 2022 - Elsevier
Background Cognitive manifestations associated with Severe Acute Respiratory Syndrome
by Coronavirus 2 (SARS-CoV-2) are yet to be described in the existing literature. The aim of …
by Coronavirus 2 (SARS-CoV-2) are yet to be described in the existing literature. The aim of …
The use of stem cell-derived organoids in disease modeling: an update
Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …
during the past decade. They are three-dimensional in vitro culturing models that originate …
Human cerebral organoids—a new tool for clinical neurology research
OL Eichmüller, JA Knoblich - Nature Reviews Neurology, 2022 - nature.com
The current understanding of neurological diseases is derived mostly from direct analysis of
patients and from animal models of disease. However, most patient studies do not capture …
patients and from animal models of disease. However, most patient studies do not capture …
Amyloid processing in COVID‐19‐associated neurological syndromes
SARS‐CoV‐2 infection can damage the nervous system with multiple neurological
manifestations described. However, there is limited understanding of the mechanisms …
manifestations described. However, there is limited understanding of the mechanisms …
Revolutionizing disease modeling: the emergence of organoids in cellular systems
R Silva-Pedrosa, AJ Salgado, PE Ferreira - Cells, 2023 - mdpi.com
Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …
through well-established protocols, while avoiding the ethical restrictions associated with …
Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?
Abstract The pandemic of Coronavirus Disease 2019 (COVID-19) presents the world with
the medical challenge associated with multifactorial nature of this pathology. Indeed COVID …
the medical challenge associated with multifactorial nature of this pathology. Indeed COVID …
Blood biomarkers for detection of brain injury in COVID-19 patients
ST DeKosky, PM Kochanek, AB Valadka… - Journal of …, 2021 - liebertpub.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus attacks multiple
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …
organs of coronavirus disease 2019 (COVID-19) patients, including the brain. There are …
Human organoids and organs‐on‐chips for addressing COVID‐19 challenges
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), poses an imminent threat to our lives. Although …
syndrome coronavirus 2 (SARS‐CoV‐2), poses an imminent threat to our lives. Although …