Telomere length as a marker of biological age: state-of-the-art, open issues, and future perspectives

A Vaiserman, D Krasnienkov - Frontiers in genetics, 2021 - frontiersin.org
Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.

NL Colich, ML Rosen, ES Williams… - Psychological …, 2020 - psycnet.apa.org
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents

JA Sumner, NL Colich, M Uddin, D Armstrong… - Biological …, 2019 - Elsevier
Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …

Developmental adaptation to stress: An evolutionary perspective

BJ Ellis, M Del Giudice - Annual review of psychology, 2019 - annualreviews.org
The assumption that early stress leads to dysregulation and impairment is widespread in
developmental science and informs prevailing models (eg, toxic stress). An alternative …

Socioeconomic disadvantage and the pace of biological aging in children

L Raffington, DW Belsky, M Kothari, M Malanchini… - …, 2021 - publications.aap.org
METHODS: Saliva DNA methylation and socioeconomic circumstances were measured in
N= 600 children and adolescents aged 8 to 18 years (48% female) participating in the Texas …

Early-life adversity accelerates child and adolescent development

J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood

EJ Hamlat, AA Prather, S Horvath… - Developmental …, 2021 - Wiley Online Library
Background Given associations linking early life adversity, pubertal timing, and biological
aging, we examined the direct and indirect effects of early life trauma on adult biological …

Early-life and pubertal stress differentially modulate grey matter development in human adolescents

A Tyborowska, I Volman, HCM Niermann… - Scientific reports, 2018 - nature.com
Animal and human studies have shown that both early-life traumatic events and ongoing
stress episodes affect neurodevelopment, however, it remains unclear whether and how …

Early adversity, elevated stress physiology, accelerated sexual maturation, and poor health in females.

J Belsky, PL Ruttle, WT Boyce… - Developmental …, 2015 - psycnet.apa.org
Evolutionary-minded developmentalists studying predictive-adaptive-response processes
linking childhood adversity with accelerated female reproductive development and health …

Stressful life events and accelerated biological aging over time in youths

JA Sumner, X Gao, S Gambazza, CK Dye… - …, 2023 - Elsevier
Experiencing adversity in childhood and adolescence, including stressful life events (SLEs),
may accelerate the pace of development, leading to adverse mental and physical health …