Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

INTRODUCTION Organisms live by means of the complex, dynamic, three-dimensional (3D)
interplay between millions of components, from the molecular to the multicellular. Visualizing …

Focal adhesion kinase (FAK; also known as PTK2) was discovered three decades ago and
is now recognised as a key player in the regulation of cell–matrix adhesion and …

In the retina, like in most other brain regions, developing neurons are arranged into distinct
layers giving the mature tissue its stratified appearance. This process needs to be highly …

The assembly of the embryo's primary axis is a fundamental landmark for the establishment
of the vertebrate body plan. Although the morphogenetic movements directing cell …

Light-sheet fluorescence microscopy (LSFM) methods collectively represent the major
breakthrough in developmental bio-imaging of living multicellular organisms. They are …

Cell-extracellular matrix interactions have been studied extensively using cells cultured in
vitro. These studies indicate that focal adhesion (FA)-based cell-extracellular matrix …

Throughout embryonic development and adult life, epithelia are subjected to compressive
deformations. While these have been shown to trigger mechanosensitive responses such as …

Shape‐morphing hydrogels bear promising prospects as soft actuators and for robotics.
However, they are mostly restricted to applications in the abiotic domain due to the harsh …