B Twarowski, M Herbet - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease is one of the most commonly diagnosed cases of senile dementia in the world. It is an incurable process, most often leading to death. This disease is multifactorial …
Alzheimer's disease (AD) is the most frequent case of neurodegenerative disease and is becoming a major public health problem all over the world. Many therapeutic strategies …
A Rashad, A Rasool, M Shaheryar, A Sarfraz, Z Sarfraz… - Healthcare, 2022 - mdpi.com
Amyloid-β (Aβ) plaques and aggregated tau are two core mechanisms that contribute to the clinical deterioration of Alzheimer's disease (AD). Recently, targeted-Aβ plaque reduction …
W Cai, T Wu, N Chen - Biomolecules, 2023 - mdpi.com
The deposition of amyloid-beta (Aβ) plaques in the brain is one of the primary pathological characteristics of Alzheimer's disease (AD). It can take place 20–30 years before the onset of …
B Penke, M Szűcs, F Bogár - International Journal of Molecular Sciences, 2023 - mdpi.com
Alzheimer's disease (AD) is an incurable, progressive neurodegenerative disorder. AD is a complex and multifactorial disease that is responsible for 60–80% of dementia cases. Aging …
A phase II trial of the tau antibody semorinemab indicates that it has no clinical benefit in the earliest stages of Alzheimer disease. The repeated finding that antibody-mediated …
D Decandia, F Gelfo, E Landolfo, F Balsamo… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a rapidly growing epidemic with a heavy social and economic burden. Evidence suggests that systemic inflammation, dysregulation of the immune …
Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the presence of plaques of amyloid beta and Tau proteins. There is currently no permanent cure …
Aging is a major risk factor for numerous chronic diseases. Vaccination offers a promising strategy to combat these age-related diseases by targeting specific antigens and inducing …