Aging hallmarks and the role of oxidative stress

E Maldonado, S Morales-Pison, F Urbina, A Solari - Antioxidants, 2023 - mdpi.com
Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

The impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health

CE Lyons, M Razzoli, A Bartolomucci - Neuroscience & Biobehavioral …, 2023 - Elsevier
Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

[HTML][HTML] Artificial Intelligence in Cancer Care: From Diagnosis to Prevention and Beyond

M Farrokhi, A Moeini, F Taheri, M Farrokhi, M Mostafavi… - Kindle, 2023 - preferpub.org
Artificial Intelligence (AI) has made significant strides in revolutionizing cancer care,
encompassing various aspects from diagnosis to prevention and beyond. With its ability to …

Genomic instability and epigenetic changes during aging

L López-Gil, A Pascual-Ahuir, M Proft - International Journal of Molecular …, 2023 - mdpi.com
Aging is considered the deterioration of physiological functions along with an increased
mortality rate. This scientific review focuses on the central importance of genomic instability …

[HTML][HTML] Improving the effectiveness of anti-aging modalities by using the constrained disorder principle-based management algorithms

N Hurvitz, N Elkhateeb, T Sigawi, L Rinsky-Halivni… - Frontiers in …, 2022 - frontiersin.org
Aging is a complex biological process with multifactorial nature underlined by genetic,
environmental, and social factors. In the present paper, we review several mechanisms of …

An ELOVL2-based epigenetic clock for forensic age prediction: a systematic review

E Paparazzo, V Lagani, S Geracitano… - International Journal of …, 2023 - mdpi.com
The prediction of chronological age from methylation-based biomarkers represents one of
the most promising applications in the field of forensic sciences. Age-prediction models …

Epigenetic clocks provide clues to the mystery of uterine ageing

PI Deryabin, AV Borodkina - Human Reproduction Update, 2023 - academic.oup.com
BACKGROUND Rising maternal ages and age-related fertility decline are a global
challenge for modern reproductive medicine. Clinicians and researchers pay specific …

Sex differences in biological systems and the conundrum of menopause: Potential commonalities in post-menopausal disease mechanisms

DA Hart - International Journal of Molecular Sciences, 2022 - mdpi.com
Sex-specific differences in biology and physiology likely start at the time of conception and
progress and mature during the pre-puberty time frame and then during the transitions …

Ageing and low-level chronic inflammation: the role of the biological clock

B Colombini, M Dinu, E Murgo, S Lotti, R Tarquini… - Antioxidants, 2022 - mdpi.com
Ageing is a multifactorial physiological manifestation that occurs inexorably and gradually in
all forms of life. This process is linked to the decay of homeostasis due to the progressive …

[HTML][HTML] Epigenetic Reprogramming as a Key to Reverse Ageing and Increase Longevity

B Pereira, FP Correia, IA Alves, M Costa… - Ageing research …, 2024 - Elsevier
The pursuit for the fountain of youth has long been a fascination amongst scientists and
humanity. Ageing is broadly characterized by a cellular decline with increased susceptibility …