The unabated increase in spread of HIV infection worldwide has redoubled efforts to
discover novel antiviral and virucidal agents that might be starting points for clinical …

Two approaches to target PNAs (peptide nucleic acids) into mitochondria of HeLa cells were
compared. In the first, PNA was modified with the lipophilic cation TPP. TPP-PNA …

Abstract In human Burkitt's Lymphoma (BL) BRG cells, at (8; 14) translocation, placing c-myc
near the Eμ enhancer of the H chain locus, causes tumor expansion. Earlier, we showed that …

Peptide nucleic acids (PNAs) are synthetic homolog of nucleic acids in which the phosphate-
sugar polynucleotide backbone is replaced by a flexible polyamide. They bind …

Unlike many small molecule drugs, oligonucleotides and short interference RNA (siRNA)
are of too high mass (4000–12,000 Da) to permeate freely into mammalian cells. In addition …

Burkitt's lymphoma endemic, sporadic, and immunodeficiency immunophenotypic features. It
for extranodal sites such as gastrointestina high-intensity chemotherapy prophylaxis have …

When Zamecnik and Stephenson first proposed synthetic oligodeoxyribonucleotides as
reagents to bind to Rous sarcoma virus RNA to inhibit viral replication, they designed an …

The present invention regards oligonucleotides for modulating the expression of a gene, in
particular for modulating a gene responsible for a pathology of genetic, tumoral or viral …

In addition to a variety of other techniques used in T-cell epitope identification, mass
spectrometery coupled to liquid chromatography have now become an important and …

Nucleic acid nanotechnology benefits from the ability of RNA (or DNA) to form both
canonical Watson-Crick (WC) eg, GC and AU (T for DNA) and non-canonical base pairings …