Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of
years, it has helped humans fight diseases and protect life, health, and reproduction …

As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Oral administration of active pharmaceutical ingredients is desirable because it is easy, safe,
painless, and can be performed by patients, resulting in good medication adherence. The …

Aim The current study aimed to develop enzyme-activated charge-reversal lipid
nanoparticles (LNPs) as novel gene delivery systems. Methods Palmitic acid was covalently …

Advances in nanotechnology have generated a broad range of nanoparticles (NPs) for
numerous biomedical applications. Among the various properties of NPs are functionalities …

The mucus is a defensive barrier for different drug-loaded systems. To overcome this
obstacle, the crucial factor is the surface charge. Due to mucus negative charge behavior; it …

Pioglitazone (PZ), a highly lipophilic Class II drug with poor aqueous solubility possesses
low oral bioavailability. The oral bioavailability of pioglitazone can be improved by …

The bioavailability of poorly soluble medications can be greatly improved by the use of
nanocarriers (NCs) where; loading of drugs within NCs could improve the solubility, prevent …

The purpose of the current study was to explore the suitability of nanostructured lipid carriers
(NLCs) loaded with a model drug calycosin for the treatment of breast cancer. NLCs were …

The objective of the study was to design mucoadhesive drug-loaded nanostructured lipid
carriers (NLCs) for enhancing the bioavailability of a model BCS Class IV drug aprepitant …