Many pharmaceutically active molecules are highly lipophilic, which renders their
administration and adsorption in patients extremely challenging. Among the countless …

Introduction: Solid matrix mediated lipid nanoparticle formulations (LNFs) retain some of the
best features of ideal drug carriers necessary for improving the oral absorption and …

Lycopene belongs to carotenoid group having lipophilic nature with strong antioxidant
potential against numerous diseases. Hence, it has been used extensively in functional …

Objectives Rivaroxaban (RXB), a novel Xa inhibitor having groundbreaking therapeutic
potential. However, this drug is associated with few limitations, including its …

The potential of duloxetine-loaded solid lipid nanoparticles (DLX-SLNs) for enhanced
antidepressant activity was investigated in the current study. Nano-template engineering …

Although simvastatin (SIM) has been proven to be a powerful agent against myocardial
ischemia/reperfusion (MI/R) injury, poor water solubility, short half-life, and low …

Wound healing is one of the most challenging medical circumstances for patients.
Pathogens can infect wounds, resulting in tissue damage, inflammation, and disruption of …

Purpose Pravastatin sodium (PVS) is a hypolipidemic drug which suffers from extensive first-
pass metabolism and short half-life. Poly (d, l-lactide-co-glycolide)(PLGA) is considered a …

The present study was intended to prepare and optimize agomelatine-loaded
nanostructured lipid carriers (AGM-NLCs) for augmented in vivo antidepressant potential …

As a functional polyphenolic compound, curcumin (CUR) has limited application due to its
low solubility and bioavailability. In this work, curcumin loaded micelles self-assembled from …