Calycosin-loaded nanostructured lipid carriers: In-vitro and in-vivo evaluation for enhanced anti-cancer potential

S Arshad, MH Asim, A Mahmood, M Ijaz… - Journal of Drug Delivery …, 2022 - Elsevier
The purpose of the current study was to explore the suitability of nanostructured lipid carriers
(NLCs) loaded with a model drug calycosin for the treatment of breast cancer. NLCs were …

[HTML][HTML] Nanostructured lipid carrier-based delivery of pioglitazone for treatment of type 2 diabetes

U Ilyas, M Asif, M Wang, R Altaf, H Zafar… - Frontiers in …, 2022 - frontiersin.org
Pioglitazone (PGZ) is utilized as a therapeutic agent in the management of (type 2) diabetes
to control blood glucose levels. The existing research work was intended to make and …

S-Protected thiolated nanostructured lipid carriers exhibiting improved mucoadhesive properties

S Arshad, MH Asim, I Nazir, I Shahzadi… - International Journal of …, 2020 - Elsevier
The purpose of the present study was to design nanostructured lipid carriers (NLCs)
exhibiting improved mucoadhesive properties. First, an S-protected thiolated fatty acid …

Raloxifene-loaded solid lipid nanoparticles decorated gel with enhanced treatment potential of osteoporosis

Z Guo, P Qi, D Pei, X Zhang - Journal of Drug Delivery Science and …, 2022 - Elsevier
Osteoporosis is a common metabolic disorder associated with global morbidities and
mortalities which make it a big challenge to the public health. Despite the availability of a …

[HTML][HTML] Highly responsive chitosan-co-poly (MAA) Nanomatrices through cross-linking polymerization for solubility improvement

A Saleem, N Akhtar, MU Minhas, A Mahmood… - Gels, 2022 - mdpi.com
In this study, we report the highly responsive chitosan-based chemically cross-linked
nanomatrices, a nano-version of hydrogels developed through modified polymerization …

[HTML][HTML] Enhancing Oral Bioavailability of Simvastatin Using Uncoated and Polymer-Coated Solid Lipid Nanoparticles

AE Abd-Elghany, O El-Garhy, AA Fatease, AH Alamri… - Pharmaceutics, 2024 - mdpi.com
Simvastatin (SVA) is a well-prescribed drug for treating cardiovascular and
hypercholesterolemia. Due to the extensive hepatic first-pass metabolism and poor …

Combination of phospholipid complex and matrix dispersion

RK Chakravarti, S Kaur, SK Samal, MC Kashyap… - AAPS …, 2021 - Springer
Phospholipid complexation, despite being a successful, versatile, and burgeoning strategy,
stickiness of phospholipids leads to suboptimal dissolution rate of drugs. This work was …

[HTML][HTML] Assessment of In Vitro Release Testing Methods for Colloidal Drug Carriers: The Lack of Standardized Protocols

L Gómez-Lázaro, C Martín-Sabroso, J Aparicio-Blanco… - Pharmaceutics, 2024 - mdpi.com
Although colloidal carriers have been in the pipeline for nearly four decades, standardized
methods for testing their drug-release properties remain to be established in …

Mucoadhesive aprepitant-loaded nanostructured lipid carriers containing sulfhydryl surfactant for enhanced oral drug bioavailability

AR Hashmi, EM Eltayib, MN Qaisar, DA Bafail… - Journal of Drug Delivery …, 2024 - Elsevier
The objective of the study was to design mucoadhesive drug-loaded nanostructured lipid
carriers (NLCs) for enhancing the bioavailability of a model BCS Class IV drug aprepitant …

[HTML][HTML] Development of mucus-penetrating iodine loaded self-emulsifying system for local vaginal delivery

S Fida, A Jalil, R Habib, M Akhlaq, A Mahmood… - Plos one, 2022 - journals.plos.org
The major goal of this project was to formulate iodine-based self nano-emulsifying drug
delivery system to provide improve antimicrobial activity and enhanced mucosal residence …