Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Post-translational modifications (PTMs) have been proposed as a link between the oxidative
stress-inflammation-ageing trinity, thereby affecting several hallmarks of ageing …

Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

Aging is a nearly inescapable trait among organisms yet lifespan varies tremendously
across different species and spans several orders of magnitude in vertebrates alone. This …

Effective conservation and management of threatened wildlife populations require an
accurate assessment of age structure to estimate demographic trends and population …

Inferring the chronological and biological age of individuals is fundamental to population
ecology and our understanding of ageing itself, its evolution, and the biological processes …

Comparative analyses of bats indicate that hibernation is associated with increased
longevity among species. However, it is not yet known if hibernation affects biological …

Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

DNA methylation is an epigenetic modification that plays a crucial role in various regulatory
processes, including gene expression regulation, transposable element repression, and …

Age is an essential trait for understanding the ecology and management of wildlife. A
conventional method of estimating age in wild animals is counting annuli formed in the …