Harnessing immunotherapy for liver recipients with hepatocellular carcinoma: a review from a transplant oncology perspective

CM Ho, HL Chen, RH Hu… - Therapeutic Advances in …, 2019 - journals.sagepub.com
Without stringent criteria, liver transplantation for hepatocellular carcinoma (HCC) can lead
to high cancer recurrence and poor prognosis in the current treatment context. Checkpoint …

Identification of peripheral CD154+ T cells and HLA-DRB1 as biomarkers of acute cellular rejection in adult liver transplant recipients

F Boix, I Legaz, A Minhas, R Alfaro… - Clinical & …, 2021 - academic.oup.com
Decreasing graft rejection and increasing graft and patient survival are great challenges
facing liver transplantation (LT). Different T cell subsets participate in the acute cellular …

[HTML][HTML] Identifying risk profiles in liver transplant candidates and implications for induction immunosuppression

U Cillo, WO Bechstein, G Berlakovich… - Transplantation …, 2018 - Elsevier
Abstract Changes in recipient and donor characteristics are redefining the role of induction
in liver transplant recipients. Older recipients are more common, with greater concomitant …

Liver perfusate natural killer cells from deceased brain donors and association with acute cellular rejection after liver transplantation: a time-to-rejection analysis

D Pagano, E Badami, PG Conaldi, A Seidita… - …, 2019 - journals.lww.com
Background The ability to predict which recipients will successfully complete their
posttransplant clinical course, which is crucial for liver transplant (LT) programs. The …

Acute liver allograft rejection after living donor liver transplantation: risk factors and patient survival

Q Wei, K Wang, Z He, Q Ke, X Xu, S Zheng - The American Journal of the …, 2018 - Elsevier
Background Acute rejection (AR) is an important problem after liver transplantation. We aim
to evaluate the incidence and risk factors of AR and to identify significant prognostic factors …

Recipient risk factors for acute cellular rejection after orthotopic liver transplant‐a single‐center, retrospective study

D Choi, M Liu, D Guttikonda, K Galen… - Transplant …, 2020 - Wiley Online Library
The use of model for end‐stage liver disease (MELD) score for liver allocation has resulted
in transplanting sicker patients. As such, it is unclear whether the risk factors and severity of …

Safety of tacrolimus monotherapy within 12 months after liver transplantation in the era of reduced tacrolimus and mycophenolate mofetil: National Registry Study

DG Kim, SH Kim, S Hwang, SK Hong, JH Ryu… - Journal of Clinical …, 2022 - mdpi.com
Tacrolimus monotherapy is accepted as a feasible option during early post-liver
transplantation as per current international consensus guidelines. However, its effects in the …

Evaluating the Incidence and Risk Factors for Acute Cellular Rejection in a Steroid Sparing Liver Transplant Center

X Zhang, A Lichvar, C Chan… - Annals of …, 2023 - journals.sagepub.com
Background: Corticosteroids has been the mainstay of immunosuppression (IMS) following
liver transplant (LT). With the advent of more potent IMS, complete steroid withdrawal has …

Combination of everolimus and low-dose tacrolimus controls histological liver allograft injury as sufficiently as high-dose tacrolimus

EA Bosselmann, F Dranicki… - Frontiers in …, 2023 - frontiersin.org
Introduction The combination of everolimus (EVR) and low-dose tacrolimus (lowTAC)
prevents T cell-mediated rejection of liver grafts as sufficiently as high-dose tacrolimus …

[PDF][PDF] Investigating the phenotype and functional roles of human liver-resident natural killer (NK) cells

G Jameson - 2022 - tara.tcd.ie
Tissue resident immune cells have been described in a number of different tissues including
the lungs294, skin295, uterus260, gut296 and the liver121. They are phenotypically distinct …