miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy

MT Di Martino, C Riillo, F Scionti, K Grillone, N Polerà… - Cancers, 2021 - mdpi.com
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …

Long non-coding RNAs in brain tumors: roles and potential as therapeutic targets

SH Kim, KH Lim, S Yang, JY Joo - Journal of hematology & oncology, 2021 - Springer
Brain tumors are associated with adverse outcomes despite improvements in radiation
therapy, chemotherapy, and photodynamic therapy. However, treatment approaches are …

The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma

W Wang, Z Lu, M Wang, Z Liu, B Wu, C Yang… - Frontiers in …, 2022 - frontiersin.org
Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Identification of immune-related lncRNA prognostic signature and molecular subtypes for glioblastoma

W Yu, Y Ma, W Hou, F Wang, W Cheng, F Qiu… - Frontiers in …, 2021 - frontiersin.org
Background Glioblastoma multiforme (GBM) is extensively genetically and transcriptionally
heterogeneous, which poses challenges for classification and management. Long …

A novel lncRNA panel related to ferroptosis, tumor progression, and microenvironment is a robust prognostic indicator for glioma patients

Y He, Y Ye, W Tian, H Qiu - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Objective: To establish a lncRNA panel related to ferroptosis, tumor progression, and
microenvironment for prognostic estimation in patients with glioma. Methods: LncRNAs …

Molecular subtypes and prognostic signature of pyroptosis-related lncRNAs in glioma patients

G Tanzhu, N Li, Z Li, R Zhou, L Shen - Frontiers in Oncology, 2022 - frontiersin.org
The relationship between pyroptosis-related long non-coding RNAs (pyroptosis-related
lncRNAs) and glioma prognosis have not been studied clearly. Basing on The Cancer …

Promoting prognostic model application: a review based on gliomas

X Liang, Z Wang, Z Dai, H Zhang, Q Cheng… - Journal of …, 2021 - Wiley Online Library
Malignant neoplasms are characterized by poor therapeutic efficacy, high recurrence rate,
and extensive metastasis, leading to short survival. Previous methods for grouping …

Coding of glioblastoma progression and therapy resistance through long noncoding RNAs

A Zottel, N Šamec, A Videtič Paska, I Jovčevska - Cancers, 2020 - mdpi.com
Glioblastoma is the most aggressive and lethal primary brain malignancy, with an average
patient survival from diagnosis of 14 months. Glioblastoma also usually progresses as a …

Mechanisms of long non-coding RNAs in biological characteristics and aerobic glycolysis of glioma

N Zhao, J Zhang, Q Zhao, C Chen, H Wang - International Journal of …, 2021 - mdpi.com
Glioma is the most common and aggressive tumor of the central nervous system. The
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …

Identification of a fibroblast-related prognostic model in glioma based on bioinformatics methods

H Zhang, Y Huang, E Yang, X Gao, P Zou, J Sun… - Biomolecules, 2022 - mdpi.com
Background: Glioma is the most common primary tumor of the central nervous system with a
high lethality rate. This study aims to mine fibroblast-related genes with prognostic value and …