Driving factors of neuronal ferroptosis

J Jacquemyn, I Ralhan, MS Ioannou - Trends in Cell Biology, 2024 - cell.com
Ferroptosis is an oxidative form of iron-dependent cell death characterized by the
accumulation of lipid peroxides on membranes. Iron and lipids containing polyunsaturated …

Research progress of ferroptosis in Parkinson's disease: a bibliometric and visual analysis

Y Lu, Y Chen, Z Jiang, Y Ge, R Yao, S Geng… - Frontiers in Aging …, 2023 - frontiersin.org
Background In recent years, the role of ferroptosis in Parkinson's disease (PD) has become
a research hotspot based on evidence of abnormal iron deposition and lipid peroxidation …

The role of cellular defense systems of ferroptosis in Parkinson's disease and Alzheimer's disease

J Chu, J Li, L Sun, J Wei - International Journal of Molecular Sciences, 2023 - mdpi.com
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common rapidly
developing neurodegenerative diseases that lead to serious health and socio-economic …

Impact of curcumin on ferroptosis‐related genes in colorectal cancer: Insights from in‐silico and in‐vitro studies

AA Firouzjaei, SH Aghaee‐Bakhtiari… - Cell Biochemistry …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is responsible for a significant number of cancer‐related fatalities
worldwide. Researchers are investigating the therapeutic potential of ferroptosis, a type of …

Uncovering ferroptosis in Parkinson's disease via bioinformatics and machine learning, and reversed deducing potential therapeutic natural products

P Wang, Q Chen, Z Tang, L Wang, B Gong, M Li… - Frontiers in …, 2023 - frontiersin.org
Objective: Ferroptosis, a novel form of cell death, is closely associated with excessive iron
accumulated within the substantia nigra in Parkinson's disease (PD). Despite extensive …

Selenium mitigates ferroptosis-mediated dopaminergic cell death by regulating the Nrf2/GPX4 pathway

YJ Jung, H Choi, E Oh - Neuroscience Letters, 2023 - Elsevier
Parkinson's disease (PD) is the second most prevalent progressive neurodegenerative
disorder and is observed only less frequently than Alzheimer's disease [1]. Two major …

[HTML][HTML] Eldecalcitol protected osteocytes against ferroptosis of D-gal-induced senescent MLO-Y4 cells and ovariectomized mice

YF Fu, YX Guo, SH Xia, TT Zhou, YC Zhao… - Experimental …, 2024 - Elsevier
Background Active vitamin D analog eldecalcitol is clinically applied in treatment of
postmenopausal osteoporosis. This study aims to determine the role of eldecalcitol in the …

Particulate Matter Induces Oxidative Stress and Ferroptosis in Human Lung Epithelial Cells

Y Ahn, YH Yim, HM Yoo - Toxics, 2024 - mdpi.com
Numerous toxicological studies have highlighted the association between urban particulate
matter (PM) and increased respiratory infections and lung diseases. The adverse impact on …

[HTML][HTML] The Molecular Mechanism of ferroptosis and Its Relationship with Parkinson's Disease

Y Su, Y Jiao, Q Wang, X Chen - Brain Research Bulletin, 2024 - Elsevier
Neurodegenerative diseases such as Parkinson's disease (PD) have complex pathogenetic
mechanisms. Genetic, age, and environmental factors are all related to PD. Due to the …

Downregulation of DDIT4 ameliorates abnormal behaviors in autism by inhibiting ferroptosis via the PI3K/Akt pathway

T Luo, S Chen, Y Ruan, H Chen, Y Chen, Y Li… - Biochemical and …, 2023 - Elsevier
Autism spectrum disorder (ASD) is a complex disease with unclear etiology. Studies have
shown that ferroptosis is also related to ASD progression, but the specific mechanism is still …