Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …

The conundrum of 'long-COVID-19: a narrative review

M Garg, M Maralakunte, S Garg, S Dhooria… - … journal of general …, 2021 - Taylor & Francis
COVID-19 is an ongoing pandemic with many challenges that are now extending to its
intriguing long-term sequel.'Long-COVID-19ʹ is a term given to the lingering or protracted …

Post-acute effects of SARS-CoV-2 infection in individuals not requiring hospital admission: a Danish population-based cohort study

LC Lund, J Hallas, H Nielsen, A Koch… - The Lancet Infectious …, 2021 - thelancet.com
Background Individuals admitted to hospital for COVID-19 might have persisting symptoms
(so-called long COVID) and delayed complications after discharge. However, little is known …

Healing after COVID-19: are survivors at risk for pulmonary fibrosis?

LT McDonald - … Journal of Physiology-Lung Cellular and …, 2021 - journals.physiology.org
The novel SARS-CoV-2 coronavirus, which is responsible for COVID-19 disease, was first
reported in Wuhan, China, in December of 2019. The virus rapidly spread, and the World …

Epidemiology and organ specific sequelae of post-acute COVID19: a narrative review

E Korompoki, M Gavriatopoulou, RS Hicklen… - Journal of Infection, 2021 - Elsevier
Objectives “Long COVID”, a term coined by COVID-19 survivors, describes persistent or new
symptoms in a subset of patients who have recovered from acute illness. Globally, the …

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
Balanced immune regulation is crucial for recognizing an invading pathogen, its killing, and
elimination. Toll‐like receptors (TLRs) are the key regulators of the innate immune system. It …

Role of JAK/STAT in interstitial lung diseases; molecular and cellular mechanisms

P Montero, J Milara, I Roger, J Cortijo - International journal of molecular …, 2021 - mdpi.com
Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …

Post-COVID-19 syndrome: involvement and interactions between respiratory, cardiovascular and nervous systems

V Visco, C Vitale, A Rispoli, C Izzo, N Virtuoso… - Journal of clinical …, 2022 - mdpi.com
Though the acute effects of SARS-CoV-2 infection have been extensively reported, the long-
term effects are less well described. Specifically, while clinicians endure to battle COVID-19 …

A systematic review and meta‐analysis of long‐term sequelae of COVID‐19 2‐year after SARS‐CoV‐2 infection: a call to action for neurological, physical, and …

M Rahmati, R Udeh, DK Yon, SW Lee… - Journal of Medical …, 2023 - Wiley Online Library
Long‐term sequelae conditions of COVID‐19 at least 2‐year following SARS‐CoV‐2
infection are unclear and little is known about their prevalence, longitudinal trajectory, and …

The role of macrophages in the development of acute and chronic inflammatory lung diseases

JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
Macrophages play an important role in the innate and adaptive immune responses of organ
systems, including the lungs, to particles and pathogens. Cumulative results show that …