Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Epigenetic dysregulation emerges as a critical hallmark and driving force of aging. Although
still an evolving field with much to explore, it has rapidly gained significance by providing …

The primate frontal lobe (FL) is sensitive to aging-related neurocognitive decline. However,
the aging-associated molecular mechanisms remain unclear. Here, using physiologically …

Our understanding of the molecular basis for cellular senescence remains incomplete,
limiting the development of strategies to ameliorate age-related pathologies by preventing …

Internal modifications of mRNA have emerged as widespread and versatile regulatory
mechanism to control gene expression at the post-transcriptional level. Most of these …

RNA modifications have emerged as important mechanisms of gene regulation.
Developmental, metabolic, and cell cycle regulatory processes are all affected by …

Abstract N6‐methyladenosine (m6A) is a dynamic and reversible RNA modification that has
emerged as a crucial player in the life cycle of RNA, thus playing a pivotal role in various …

The liver is one of the few organs that retain the capability to regenerate in adult mammals.
This regeneration process is mainly facilitated by the dynamic behavior of hepatocytes …

Epigenetic methylation has been shown to play an important role in transcriptional
regulation and disease pathogenesis. Recent advancements in detection techniques have …

Cardiac aging constitutes a significant risk factor for cardiovascular diseases prevalent
among the elderly population. Urgent attention is required to prioritize preventive and …