A comprehensive overview of Infinium HumanMethylation450 data processing
S Dedeurwaerder, M Defrance, M Bizet… - Briefings in …, 2014 - academic.oup.com
Infinium HumanMethylation450 beadarray is a popular technology to explore DNA
methylomes in health and disease, and there is a current explosion in the use of this …
methylomes in health and disease, and there is a current explosion in the use of this …
[HTML][HTML] Genetic–epigenetic interactions in cis: a major focus in the post-GWAS era
Studies on genetic–epigenetic interactions, including the mapping of methylation
quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation …
quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation …
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. In the present study …
understand mechanisms underpinning gene regulation and disease. In the present study …
[HTML][HTML] Engineering triangular carbon quantum dots with unprecedented narrow bandwidth emission for multicolored LEDs
F Yuan, T Yuan, L Sui, Z Wang, Z Xi, Y Li, X Li… - Nature …, 2018 - nature.com
Carbon quantum dots (CQDs) have emerged as promising materials for optoelectronic
applications on account of carbon's intrinsic merits of high stability, low cost, and …
applications on account of carbon's intrinsic merits of high stability, low cost, and …
[HTML][HTML] DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
Mitotic cell division increases tumour mutation burden and copy number load, predictive
markers of the clinical benefit of immunotherapy. Cell division correlates also with genomic …
markers of the clinical benefit of immunotherapy. Cell division correlates also with genomic …
Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes
Abstract Illumina Infinium DNA Methylation BeadChips represent the most widely used
genome-scale DNA methylation assays. Existing strategies for masking Infinium probes …
genome-scale DNA methylation assays. Existing strategies for masking Infinium probes …
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
Abstract Motivation: The recently released Infinium HumanMethylation450 array (the
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …
[HTML][HTML] The transcriptional landscape of age in human peripheral blood
MJ Peters, R Joehanes, LC Pilling… - Nature …, 2015 - nature.com
Disease incidences increase with age, but the molecular characteristics of ageing that lead
to increased disease susceptibility remain inadequately understood. Here we perform a …
to increased disease susceptibility remain inadequately understood. Here we perform a …
Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes
Given the tissue-specific nature of epigenetic processes, the assessment of disease-relevant
tissue is an important consideration for epigenome-wide association studies (EWAS). Little …
tissue is an important consideration for epigenome-wide association studies (EWAS). Little …
[HTML][HTML] Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits
The identification of genes and regulatory elements underlying the associations discovered
by GWAS is essential to understanding the aetiology of complex traits (including diseases) …
by GWAS is essential to understanding the aetiology of complex traits (including diseases) …