Human DNA topoisomerases are essential for crucial cellular processes, including DNA
replication, transcription, chromatin condensation, and maintenance of its structure. One of …

Background Cellular senescence occurs throughout life and can play beneficial roles in a
variety of physiological processes, including embryonic development, tissue repair, and …

Objective To analyze the impact of global population aging on cancer epidemiology, with a
focus on the incidence and mortality rates among individuals aged 60 years and above …

Epigenetic dynamics of aging and cancer development: current... : Current Opinion in Oncology
Epigenetic dynamics of aging and cancer development: current concepts from studies …

Pancreatic adenocarcinoma (PAAD) is one of the deadliest malignancies. Aging is
described as the degeneration of physiological function, which is complexly correlated with …

Studies on somatic mutations in cloned animals have revealed slight genetic variances
between clones and their originals, but have yet to identify the precise effects of these …

Simple Summary Along with a complete cure for cancer, health-related quality of life
(HRQoL) is equally important to many cancer patients and survivors. Uncertainty exists …

Due to the growth of the elderly population, age-related neurological disorders are an
increasing problem. Aging begins very gradually and later leads to several neurological …

Animal cells display great diversity in their shape. These morphological characteristics result
from crosstalk between the plasma membrane and the force-generating capacities of the …

Optimal recovery of immune competence after periods of hematopoietic insults or stress is
crucial to re-establish patient response to vaccines, pathogens and tumor antigens. This is …