Biological clocks as age estimation markers in animals: a systematic review and meta‐analysis

LS Le Clercq, A Kotzé, JP Grobler… - Biological …, 2023 - Wiley Online Library
Various biological attributes associated with individual fitness in animals change predictably
over the lifespan of an organism. Therefore, the study of animal ecology and the work of …

DNA methylation predicts age and provides insight into exceptional longevity of bats

GS Wilkinson, DM Adams, A Haghani, AT Lu… - Nature …, 2021 - nature.com
Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

High social status males experience accelerated epigenetic aging in wild baboons

JA Anderson, RA Johnston, AJ Lea, FA Campos… - Elife, 2021 - elifesciences.org
Aging, for virtually all life, is inescapable. However, within populations, biological aging rates
vary. Understanding sources of variation in this process is central to understanding the …

Age estimation in fishes using epigenetic clocks: Applications to fisheries management and conservation biology

F Piferrer, D Anastasiadi - Frontiers in Marine Science, 2023 - frontiersin.org
The distribution of age classes is a key demographic parameter of populations and thus
proper age estimation is crucial for fisheries management and for conservation biology. Age …

Nonlethal age estimation of three threatened fish species using DNA methylation: Australian lungfish, Murray cod and Mary River cod

B Mayne, T Espinoza, D Roberts… - Molecular Ecology …, 2021 - Wiley Online Library
Age‐based demography is fundamental to management of wild fish populations. Age
estimates for individuals can determine rates of change in key life‐history parameters such …

A clockwork fish: Age prediction using DNA methylation‐based biomarkers in the European seabass

D Anastasiadi, F Piferrer - Molecular Ecology Resources, 2020 - Wiley Online Library
Age‐related changes in DNA methylation do occur. Taking advantage of this, mammalian
and avian epigenetic clocks have been constructed to predict age. In fish, studies on age …

Age prediction of green turtles with an epigenetic clock

B Mayne, W Mustin, V Baboolal… - Molecular Ecology …, 2022 - Wiley Online Library
Age is a fundamental life history attribute that is used to understand the dynamics of wild
animal populations. Unfortunately, most animals do not have a practical or nonlethal method …

[HTML][HTML] A genomic predictor of lifespan in vertebrates

B Mayne, O Berry, C Davies, J Farley, S Jarman - Scientific Reports, 2019 - nature.com
Biological ageing and its mechanistic underpinnings are of immense biomedical and
ecological significance. Ageing involves the decline of diverse biological functions and …

[HTML][HTML] A DNA methylation age predictor for zebrafish

B Mayne, D Korbie, L Kenchington, B Ezzy… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Abstract Changes in DNA methylation at specific CpG sites have been used to build
predictive models to estimate animal age, predominantly in mammals. Little testing for this …

DNA methylation as a tool to explore ageing in wild roe deer populations

J Lemaître, B Rey, J Gaillard, C Régis… - Molecular ecology …, 2022 - Wiley Online Library
DNA methylation‐based biomarkers of ageing (epigenetic clocks) promise to lead to new
insights into evolutionary biology of ageing. Relatively little is known about how the natural …